Reprogramming NAD(P)

Song Wang, Beibei Zhang, Wenhao Hu, Huan Wang, Jing Zhao, Hui-Jie Pan

Abstract read

In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Song WangState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry, Nanjing University, Nanjing, People's Republic of China.

Beibei ZhangState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry, Nanjing University, Nanjing, People's Republic of China.

Wenhao HuState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry, Nanjing University, Nanjing, People's Republic of China.

Huan WangState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry, Nanjing University, Nanjing, People's Republic of China.ORCID 0000-0003-1585-6760

Jing ZhaoState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry, Nanjing University, Nanjing, People's Republic of China.

Hui-Jie PanState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry, Nanjing University, Nanjing, People's Republic of China.ORCID 0000-0003-3737-3524

Funding

Fundamental Research Funds for the Central Universities 0205/14380370National Key Research and Development Program of China 2022YFA1505600Natural Science Foundation of Jiangsu Province BK20232016Natural Science Foundation of Jiangsu Province JSSCTD202309State Key Laboratory of Coordination Chemistry

6 · The paper itself

Abstract

Efficient integration of non-natural catalytic motifs into protein scaffolds remains a central challenge in artificial enzyme design. Here we report aniline adenine dinucleotide (AnAD), a NAD

Indexed as

IminesNADNADPBiocatalysisStereoisomerismIminesNADNADPartificial enzymeenantioselective protonationFriedel‐Crafts alkylationiminiumNAD+ cofactor

Identifiers

PMID42261918

DOI10.1002/anie.2116720

PMCPMC13383257

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.