Evidence map›Paper›PMID 42261917›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Glutathione-Induced In Situ Oxygen Vacancies in FeOOH Nanospindles for Boosting Sonocatalytic Tumor Therapy.

Xinyu Ma, Zhuang Yang, Sainan Liu, Zhendong Liu, Jing Li, Mingkai Yang, Zhihua Lai, Pan Zheng, Binbin Ding, Ping'an Ma and 1 more

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xinyu MaKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, China.
Zhuang YangKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, China.
Sainan LiuKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, China.
Zhendong LiuKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, China.
Jing LiKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, China.
Mingkai YangKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, China.
Zhihua LaiKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, China.
Pan ZhengCollege of Material Sciences and Chemical Engineering, Key Laboratory of Superlight Materials & Surface Technology of Ministry of Education, Harbin Engineering University, Harbin, Heilongjiang, China.
Binbin DingKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, China.ORCID 0000-0002-3717-857X
Ping'an MaKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, China.
Jun LinKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, China.ORCID 0000-0001-9572-2134

Funding

Changbai Talent Program of Jilin Province 202441109Heilongjiang Touyan Innovation Team Program TY24003Major Project of the State Key Laboratory in Changchun 23GZZ04National Natural Science Foundation of China 22575067National Natural Science Foundation of China 52372273National Natural Science Foundation of China 52422219National Natural Science Foundation of China 52432008Natural Science Foundation of Heilongjiang Province YQ2024E033Science and Technology Development Planning Project of Jilin Province 20260101009JJ
6 · The paper itself

Abstract

Defect engineering can enhance carrier separation in sonocatalysts to boost reactive oxygen species (ROS) generation; however, the current methods still rely on in vitro physicochemical defect introduction that lacks tumor specificity and poses a risk of off-target activation. Herein, we developed FeOOH nanospindles in which glutathione (GSH) within tumor cells triggers the formation of in situ oxygen vacancies (O

Indexed as

Antineoplastic AgentsFerric CompoundsCatalysisReactive Oxygen SpeciesTumor MicroenvironmentAntineoplastic AgentsFerric CompoundsReactive Oxygen SpeciesFeOOH nanospindleferroptosisin situ‐oxygen vacanciessonocatalytic therapytumor microenvironment‐responsive

Identifiers

PMID42261917
PMCPMC13427107

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.