Observational study in Hypertension (Dallas, Tex. : 1979), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02231398 (Pregnancy as a Window to Future Cardiovascular Health), which is not on this map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pregnancy as a Window to Future Cardiovascular Health: Adverse Pregnancy Outcomes as Predictors of Increased Risk Factors for Cardiovascular Disease
TypeobservationalSponsorRTI InternationalRan2014 to 2020Enrolled4,509ConditionsPregnancy Complicated by Cardiovascular Disorders as Postpartum Condition, Delivered During Previous Episode, Breathing-Related Sleep Disorder
3 · Its place in the literature
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The record
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
22 authors.
Laura H BrubakerDivision of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences (L.H.B., H.S.), University of Pittsburgh School of Medicine, PA.ORCID 0009-0004-8762-4429
Janet M CatovUPMC Magee-Womens Research Institute, University of Pittsburgh School of Medicine, PA (J.M.C.).ORCID 0000-0002-9551-851X
C Noel Bairey MerzSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA (C.N.B.M.).ORCID 0000-0002-9933-5155
Bethany Barone GibbsDepartment of Epidemiology, West Virginia University School of Public Health, Morgantown (B.B.G.).ORCID 0000-0002-0732-6148
Whitney BookerDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York City (W.B.).ORCID 0000-0003-0405-069X
Judith H ChungDivision of Maternal Fetal Medicine, Department of Obstetrics & Gynecology, UC Irvine Health, CA (J.H.C.).
Philip GreenlandDepartment of Preventive Medicine and Department of Medicine (P.G., A.H.), Northwestern University, Feinberg School of Medicine, Chicago, IL.ORCID 0000-0002-6327-2439
William A GrobmanDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Brown University, RI (W.A.G., A.H.).
Sadiya S KhanDepartments of Cardiology and Epidemiology (S.S.K.), Northwestern University, Feinberg School of Medicine, Chicago, IL.ORCID 0000-0003-0643-1859
Abbi LaneDepartment of Applied Exercise Science, School of Kinesiology, University of Michigan, Ann Arbor (A.L.).ORCID 0000-0001-9620-1402
Lisa D LevineMaternal-Fetal Medicine Division, Department of Obstetrics and Gynecology, Penn Medicine, University of Pennsylvania, Philadelphia (L.D.L.).ORCID 0000-0002-6811-7980
Eliza C MillerDivision of Women's Neurology, Department of Neurology (E.C.M.), University of Pittsburgh School of Medicine, PA.ORCID 0000-0002-7108-8906
Matthew F MuldoonDivision of Cardiology, Department of Medicine (M.F.M.), University of Pittsburgh School of Medicine, PA.ORCID 0000-0002-2111-6331
Mitali RayDepartment of Health Promotion and Development, University of Pittsburgh School of Nursing, PA (M.R.).ORCID 0000-0002-7175-8287
George R SaadeDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, VA (G.R.S.).ORCID 0000-0001-7925-5302
Christina M ScifresDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis (C.M.S.).
Robert M SilverDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City (R.M.S.).
Hyagriv SimhanDivision of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences (L.H.B., H.S.), University of Pittsburgh School of Medicine, PA.
Lynn M YeeDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology (L.M.Y.), Northwestern University, Feinberg School of Medicine, Chicago, IL.ORCID 0000-0002-6274-0544
Alisse HauspurgDepartment of Preventive Medicine and Department of Medicine (P.G., A.H.), Northwestern University, Feinberg School of Medicine, Chicago, IL.ORCID 0000-0001-5009-7371
Funding
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health)UM1TR004528 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI GRACE A MCCOMSEY · 2023 to 2026
$32.1M
Stress and Racial Disparities in Preeclampsia - Clues from DNA Methylomic ProfilingU01HL145358 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI Rebecca Boehm McNeil · 2020 to 2026
$24.6M
Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063036 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI PARKER, CORETTE BREEDEN · 2010 to 2015
$19.5M
Pregnancy as a Window to Future Cardiovascular Health: Adverse Pregnancy Outcomes Supplement RequestU10HL119991 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI PARKER, CORETTE BREEDEN · 2013 to 2018
$12.6M
Institute for Clinical and Translational ScienceUL1TR000153 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M · 2012 to 2015
$12.1M
Prevention of Preterm Birth in high Risk Nulliparous PatientsU10HD063047 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WAPNER, RONALD · 2010 to 2014
$1.9M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063053 · NICHD · UNIVERSITY OF UTAH · PI SILVER, ROBERT M. · 2010 to 2014
$1.7M
Preterm Birth in Nulliparous Women: An Understudied Population at Great Risk U10HD063020 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GROBMAN, WILLIAM ADAM · 2010 to 2014
$1.6M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063046 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI WING, DEBORAH A · 2010 to 2014
backgroundIsolated diastolic hypertension can precede combined systolic-diastolic hypertension, suggesting isolated diastolic hypertension may be a risk factor for adverse cardiovascular outcomes. Little is known about the prevalence of hypertensive subtypes (isolated diastolic, isolated systolic, or combined systolic-diastolic hypertension) in the years after first pregnancy, and whether these differ after hypertensive disorder of pregnancy.
methodsThis is a secondary analysis (conducted 2023-2024) of the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be Heart Health Study. Nulliparas were enrolled at 8 US clinical sites from 2010 to 2013; participants who completed the Heart Health Study visit 2 to 7 years after pregnancy were eligible. Blood pressures were elevated at the visit if systolic was ≥130 mm Hg and diastolic ≥80 mm Hg. Multinomial logistic regression relative risk models were adjusted for age, body mass index, race, and time from pregnancy to visit.
resultsFour thousand three hundred two participants were included. Mean age at Heart Health Study visit was 30.7 years (SD, 5.6 years); 812 (19%) had elevated blood pressure. Isolated diastolic hypertension was most prevalent (n=627; 15%). Compared with normotensive pregnancy, hypertensive disorders of pregnancy were associated with combined systolic-diastolic (adjusted risk ratio, 3.09 [95% CI, 2.21-4.31]) and isolated diastolic hypertension (adjusted risk ratio, 1.65 [95% CI, 1.36-2.00]).
conclusionsIsolated diastolic hypertension is the most prevalent hypertensive subtype after first pregnancy. Women with hypertensive disorders of pregnancy had increased risk of combined systolic-diastolic and isolated diastolic hypertension. Given the high prevalence of isolated diastolic hypertension found in this cohort, postpartum women represent a subgroup with opportunity for cardiovascular risk reduction. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT02231398.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Subtypes of Hypertension 2 to 7 Years After First Pregnancy. · full record | OpenQuestion