ArticleHealth science reports2026
Effects of Egg White Powder Supplementation on Nutritional Status, Biochemical Profile, and Oxidative Stress Markers in Diabetic Hemodialysis Patients; A Double-Blind Randomized Controlled Trial.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Background and Aims: Protein-energy wasting (PEW) and oxidative stress (OS) frequently occur as complications in patients undergoing hemodialysis (HD), especially among those diagnosed with type 2 diabetes mellitus (T2DM). Egg white powder (EWP) is a low-phosphorus, high- biological value protein source that may help improve nutritional and oxidative balance. This study aimed to evaluate the impacts of EWP supplementation on nutritional status, biochemical parameters, and OS markers in diabetic HD patients. Methods: In this double-blind, placebo-controlled trial, 39 adult T2DM patients on HD were randomly assigned to receive either EWP (30 g; 22 g protein; 3 days/week) or a cocoa-flavored placebo during HD sessions for 8 weeks. Primary outcomes included Nutritional indicators (BMI, dietary intake, serum albumin, phosphorus, and OS markers-total antioxidant capacity (TAC), superoxide dismutase (SOD), and malondialdehyde (MDA). ANCOVA adjusted for baseline values, body mass index, dietary intake, energy intake, and physical activity was used for group comparisons. Results: Protein intake increased significantly in the EWP group, while phosphorus decreased. Serum albumin rose from 3.65 ± 0.62 to 4.15 ± 0.69 g/dL ( Conclusion: EWP supplementation improved protein intake, albumin levels, lipid control, and antioxidant capacity in diabetic HD patients without increasing phosphorus burden. EWP may serve as a safe, functional nutritional supplement in renal nutrition therapy.
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