ReviewCureus2026
Determining the Effects of Lifestyle Factors Including Smoking, Alcohol Consumption, Physical Activity, and Diet on the Risk and Progression of Dementia: A Systematic Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dementia and cognitive decline among older adults are increasingly considered as a significant health burden with a high level of personal, societal, and economic implications. Understanding the influence of lifestyle factors and potential lifestyle modifications on the risk and progression of dementia may aid in offering a non-pharmacological approach to reducing this public health challenge. This study explores the impact of key lifestyle factors - diet, physical activity, smoking, and alcohol consumption - on both the risk and progression of dementia. A systematic literature review was conducted using a predefined search strategy. Studies were identified through searches of the databases PubMed, Scopus, Web of Science, Embase, Medline, and CINAHL. Studies published between 2014 and 2024 were included to capture recent evidence. The quality of the selected studies was assessed using the Newcastle-Ottawa Scale (NOS) for cohort studies and the Joanna Briggs Institute (JBI) Critical Appraisal Checklist for cross-sectional studies. A total of 1,135 studies were initially identified; 12 met the inclusion criteria and were critically reviewed. The findings suggest that each lifestyle factor exerts an influence on the risk and progression of dementia, albeit to varying degrees. Further research is needed to deepen the understanding of these relationships and inform targeted preventive strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.