ArticleClinical ophthalmology (Auckland, N.Z.)2026
Outcomes of Synthetic Corneal Endothelial Implant in Patients with Corneal Oedema with or without Prior Endothelial Keratoplasty: A Case Series.
Article in Clinical ophthalmology (Auckland, N.Z.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Purpose: To evaluate the safety and efficacy of artificial endothelial layer (EndoArt Methods: This retrospective, non-comparative study reviewed medical records of consecutive patients who underwent EndoArt Results: Nine eyes of nine patients were included (mean age: 72±17 years; 55% female). Four patients (44%) had previous failed endothelial keratoplasty. Mean follow-up was 27±14 weeks. Mean baseline CCT decreased significantly from 780±106μm [95% CI: 710.0, 861.3μm] to 574±107μm [95% CI 502.8, 643.1μm], postoperatively (adjusted for implant thickness), representing a 35% reduction (265±89 μm; 95% CI: -338.8 to -190.8μm; p<0.01). Mean BCDVA improved from 2.28±0.54 LogMAR [95% CI 1.87, 2.71 LogMAR] to 1.16±0.79 LogMAR [95% CI 0.55, 1.78 LogMAR]. Three patients (33%) achieved postoperative BCDVA of ≤0.5 LogMAR. Two patients (22%) required re-suturing; no rebubbling was performed. No endophthalmitis, inflammatory reactions, or chronic intraocular pressure elevation occurred. Conclusion: Artificial corneal endothelial implant was associated with significant reduction in corneal thickness (35%) and improvements in visual acuity in eyes with chronic endothelial dysfunction, with or without prior endothelial keratoplasty. The procedure was feasible in complex eyes with prior failed endothelial keratoplasty and glaucoma drainage devices. EndoArt
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