Evidence map›Paper›PMID 42261383›Full record

ArticleClinical and experimental gastroenterology2026

Irritable Bowel Syndrome Prevalence in Patients with Inflammatory Bowel Disease in Remission: Single-Center Experience.

Olga Golubovic, Tamara Knezevic Ivanovski, Djordje Kralj, Milos Mitrovic, Aleksandar Milić, Petar Svorcan, Srdjan Markovic

Abstract read
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Article in Clinical and experimental gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Olga GolubovicDepartment of Gastroenterology and Hepatology, University Hospital Medical Center Zvezdara, Belgrade, Serbia.ORCID 0009-0001-1964-1620
Tamara Knezevic IvanovskiDepartment of Gastroenterology and Hepatology, University Hospital Medical Center Zvezdara, Belgrade, Serbia.
Djordje KraljDepartment of Gastroenterology and Hepatology, University Hospital Medical Center Zvezdara, Belgrade, Serbia.ORCID 0009-0005-9153-2153
Milos MitrovicDepartment of Gastroenterology and Hepatology, University Hospital Medical Center Zvezdara, Belgrade, Serbia.
Aleksandar MilićDepartment of Gastroenterology and Hepatology, University Hospital Medical Center Zvezdara, Belgrade, Serbia.
Petar SvorcanDepartment of Gastroenterology and Hepatology, University Hospital Medical Center Zvezdara, Belgrade, Serbia.ORCID 0000-0001-7627-812X
Srdjan MarkovicDepartment of Gastroenterology and Hepatology, University Hospital Medical Center Zvezdara, Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD) are characterized by features of abdominal pain and changes in bowel habits, making it hard to differentiate between the two. Early studies that estimated prevalence of IBS in IBD patients defined remission based only on clinical scores, potentially overestimating IBS symptoms and underestimating subclinical inflammation. The aim of this study was to determine prevalence of IBS in IBD patients who are treated with biologics and have reached clinical, biologic and endoscopic remission, thereby applying a more stringent definition of remission. Methods: This single-center cross-sectional study included 136 patients (68 patients with Crohn's disease and 68 with ulcerative colitis) who are treated with biologics from December 2022 to June 2023 and have reached clinical, biologic and endoscopic remission. Clinical remission was defined as Crohn's disease activity index (CDAI) ≤ 150 for patients with Crohn's disease (CD), and Mayo partial score ≤ 1 for patients with ulcerative colitis (UC). Biologic remission was defined as faecal calprotectin (FCP) ≤ 250 ug/g, and endoscopic remission was defined as the absence of ulcerations for CD and Mayo subscore ≤ 1 for UC patients. The presence of IBS was defined by Rome IV criteria. Results: A total of 28 (20.6%) patients in complete remission reported symptoms consistent with IBS, based on Rome IV criteria. The prevalence of IBS was higher in patients with Crohn's disease than in those with ulcerative colitis (CD 27.9% (19/68) vs UC 13.2% (9/68), Conclusion: Prevalence of IBS symptoms in IBD patients varies according to how remission is defined. When using stringent clinical, biological and endoscopic remission criteria, 20% of patients present with IBS symptoms, more commonly in those with CD.

Indexed as

IBDIBSprevalence

Identifiers

PMID42261383
PMCPMC13242762

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