Evidence map›Paper›PMID 42261197›Full record

ReviewSmall (Weinheim an der Bergstrasse, Germany)2026

Biomass Hydrogel for Wound Dressings: Design, Functionalization and Application.

Dan Xing, Jingfa Zhang, Ahmed Koubaa, Yutong Yang, Huifang Ma, Zhiheng Yang, Zhengxin Ma, Haigang Wang, Peng Li

Abstract readReview
In one paragraph

Review in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dan XingHenan Institute of Flexible Electronics (HIFE) and School of Flexible Electronics (SoFE), Henan University, Zhengzhou, China.
Jingfa ZhangState Key Laboratory of Green Papermaking and Resource Recycling, Shandong Academy of Sciences, Qilu University of Technology, Jinan, China.ORCID https://orcid.org/0000-0001-8558-9376
Ahmed KoubaaForest Research Institute, Université Du Québec en Abitibi-Témiscamingue, Rouyn-Noranda, Canada.ORCID https://orcid.org/0000-0002-7895-1901
Yutong YangHenan Institute of Flexible Electronics (HIFE) and School of Flexible Electronics (SoFE), Henan University, Zhengzhou, China.
Huifang MaHenan Institute of Flexible Electronics (HIFE) and School of Flexible Electronics (SoFE), Henan University, Zhengzhou, China.
Zhiheng YangHenan Institute of Flexible Electronics (HIFE) and School of Flexible Electronics (SoFE), Henan University, Zhengzhou, China.
Zhengxin MaHenan Institute of Flexible Electronics (HIFE) and School of Flexible Electronics (SoFE), Henan University, Zhengzhou, China.ORCID https://orcid.org/0000-0003-4646-097X
Haigang WangKey Laboratory of Bio-Based Materials Science and Technology (Ministry of Education), Northeast Forestry University, Harbin, China.ORCID https://orcid.org/0000-0001-7812-5397
Peng LiHenan Institute of Flexible Electronics (HIFE) and School of Flexible Electronics (SoFE), Henan University, Zhengzhou, China.ORCID https://orcid.org/0000-0002-5876-2177

Funding

Henan Provincial Science and Technology Foundation 252102230038National Natural Science Foundation of China 32301536National Natural Science Foundation of China 52473265Shaanxi Provincial Science Fund for Distinguished Young Scholars 2023-JC-JQ-32
6 · The paper itself

Abstract

Biomass hydrogel-based wound dressings mark a pivotal evolution in wound care, transitioning from simple protective barriers to sophisticated, multifunctional therapeutic platforms capable of actively modulating the healing microenvironment. This review summarizes the current progress in raw material selection, structural and functional design, and application of biomass hydrogels for different types of wounds. Biomacromolecules (such as polysaccharides, proteins, and polyphenols) used for synthesizing hydrogels were almost derived from plants, animals, and microorganisms. This review critically evaluates advanced functionalization strategies, including chemical modifications by incorporating functional additives such as nanoparticles, bioactive peptides, polysaccharides, and essential oils, and the development of advanced structural designs of hydrogel dressings (e.g., layered, porous, and bio-inspired architectures), emphasizing how they can be tailored for specific wound healing applications. The synergy among materials, functional additives, and structural designs empowers hydrogel dressings with broad multifunctional capabilities, demonstrating remarkable efficacy in treating wounds, including burns, diabetic ulcers, and surgical injuries. Additionally, the emerging frontiers of smart and responsive hydrogels that respond to the microenvironment for on-demand therapeutic release are highlighted, concluding with a discussion of the critical challenges for clinical translation.

Indexed as

BandagesBiomassHydrogelsWound HealingAnimalsHumansHydrogelsfunctional modificationhydrogel dressingsmaterialsstimuli responsivewound healing

Identifiers

PMID42261197
PMCPMC13411045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.