ReviewMini reviews in medicinal chemistry2026
Multifunctional Therapeutic Potential of Phytocomplexes from
Review in Mini reviews in medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pterocarpus Santalinus (red sandalwood) is a medicinal species native to the Eastern Ghats of South India, traditionally used in Ayurveda and Siddha for the treatment of inflammatory, gastrointestinal, dermatological, and metabolic disorders. Modern studies support its therapeutic potential against cancer, oxidative stress, infections, ulcers, and neurodegenerative diseases, highlighting its broad pharmacological significance. The diverse pharmacological effects of P. santalinus are attributed to its rich phytochemical profile. The plant harbors a wide array of secondary metabolites, including terpenoids, steroids, sesquiterpenes, flavonoids, benzofurans, coumarins, lignans, pterocarpans, aurones, and chalcones. These bioactive compounds function both individually and synergistically to elicit anti-inflammatory, antioxidant, anticancer, antibacterial, antiviral, wound-healing, and neuroprotective effects. Additionally, its ability to regulate metabolic pathways linked to diabetes and dyslipidemia highlights its promise for addressing non-communicable diseases. Mechanistic studies further reveal that these pharmacological actions are mediated through multiple molecular pathways, notably NF-κB, MAPK, Nrf2-ARE, and TGF-β/Smads, underscoring its multi-target mode of action. Despite its long-standing ethnopharmacological relevance and promising experimental evidence, systematic scientific investigation of P. santalinus remains limited. Future research should focus on bioassay-guided isolation, in vivo validation, safety, and pharmacokinetic evaluation, and the integration of network pharmacology, metabolomics, and sustainable cultivation to enable efficient lead discovery and conservation. In conclusion, a systematic phytochemical and pharmacological investigation of P. santalinus is essential to validate its traditional uses, establish the therapeutic value of its chemical constituents, and support its integration into mainstream pharmaceutical and commercial applications.
Indexed as
Identifiers
42261177What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.