Observational studyThe Journal of international medical research2026
Peripheral blood inflammatory indices and their association with hospitalization status in acute exacerbation of chronic obstructive pulmonary disease: A retrospective observational study.
Observational study in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
ObjectiveChronic obstructive pulmonary disease is a progressive inflammatory lung disease characterized by chronic bronchitis and emphysema. This study aimed to evaluate the levels of composite inflammatory markers, including systemic immune-inflammation index, systemic inflammatory response index, pan-immune-inflammation value, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, hemoglobin-to-red cell distribution width ratio, hemoglobin-to-monocyte ratio, and hemoglobin-to-white blood cell count ratio, in patients presenting with acute exacerbation of chronic obstructive pulmonary disease.MethodsThis retrospective observational study included patients aged ≥40 years who presented to a tertiary Chest Diseases clinic between 2022 and 2024 with acute exacerbation of chronic obstructive pulmonary disease. Patients were categorized into two groups (outpatient treatment and hospitalization groups) according to the management strategy used. Hematological parameters and composite inflammatory indices were calculated and compared between the groups.ResultsIn total, 314 patients were included; 80.3% of them were male. Hospitalized patients were significantly older and had higher white blood cell counts, C-reactive protein levels, neutrophil-to-lymphocyte ratios, platelet-to-lymphocyte ratios, systemic immune-inflammation indices, systemic inflammatory response indices, and pan-immune-inflammation values than outpatients (all
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