Evidence map›Paper›PMID 42260728›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2026

No Association Between Umbilical Cord pH and Special Educational Needs Among Children With Normal 5-Minute Apgar Scores.

Celina Myrhøj, Harman Yonis, Rikke Wiingreen, Ellen Christine Leth Løkkegaard, Christian Torp-Pedersen, Bo Mølholm Hansen

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Article in Acta paediatrica (Oslo, Norway : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Celina MyrhøjDepartment of Obstetrics and Gynecology, Copenhagen University Hospital - North Zealand, Hilleroed, Denmark.ORCID https://orcid.org/0009-0000-7201-9518
Harman YonisDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Rikke WiingreenDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Ellen Christine Leth LøkkegaardDepartment of Obstetrics and Gynecology, Copenhagen University Hospital - North Zealand, Hilleroed, Denmark.
Christian Torp-PedersenDepartment of Cardiology, Copenhagen University Hospital, North Zealand, Hilleroed, Denmark.
Bo Mølholm HansenDepartment of Paediatrics and Adolescent Medicine, Copenhagen University Hospital - North Zealand, Hilleroed, Denmark.ORCID https://orcid.org/0000-0002-3087-3983

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimMost infants with a low cord pH have reassuring 5-min Apgar scores of 7-10, but their long-term outcomes have been poorly studied. We examined whether cord pH predicted later special educational needs (SEN).

methodThis nationwide register-based study was conducted in Denmark, which provides universal cord pH screening. It comprised singletons born after 35 weeks of gestation from 2006 to 2013, with 5-min Apgar scores of 7-10 and cord pH values of < 7.0, 7.0-7.09, and ≥ 7.1. Information on SEN was obtained from national registers until June 3, 2020, when the children were 6.5-14.5 years of age. Associations between cord pH and SEN were analysed using multivariable Cox regression, and eight-year cumulative incidence estimates were calculated.

resultsWe found that 1121 of the 318 486 (0.4%) infants had cord pH values of < 7.0 and 8582 (2.7%) had 7.0-7.09. The adjusted hazard ratio for SEN was 0.95 (p = 0.73) for a cord pH of < 7.0 and 0.98 (p = 0.72) for 7.0-7.09, compared with a pH of ≥ 7.1. The eight-year cumulative incidence of SEN was similar in the groups.

conclusionsCord pH was not associated with later SEN in children born after 35 weeks of gestation who had reassuring 5-min Apgar scores.

Indexed as

Apgar ScoreEducation, SpecialFetal BloodAdolescentChildDenmarkFemaleHumansHydrogen-Ion ConcentrationInfant, NewbornMaleRegistriesApgar scoreneurodevelopmental outcomesspecial educational needsumbilical cord pHuniversal screening

Identifiers

PMID42260728
PMCPMC13552587

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