Evidence map›Paper›PMID 42260697›Full record

ArticleAdvanced healthcare materials2026

Tetrahydroxy Diboron-Enabled 3D-Printable Bioactive Hydrogel Scaffolds for Accelerated Repair of Vaginal Defects.

Yi Wang, Jinghong Jiang, Yishan Wang, Yijing Zhang, Yuedong He, Maling Gou, Zhongyi Zhu, Yifan Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi WangCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu, China.ORCID https://orcid.org/0000-0003-1758-5829
Jinghong JiangDepartment of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Yishan WangCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu, China.
Yijing ZhangDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.
Yuedong HeDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.
Maling GouDepartment of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Zhongyi ZhuDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.
Yifan WangSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, Singapore.ORCID https://orcid.org/0000-0003-2284-520X

Funding

China Scholarship Council Program 202408510215Fundamental Research Funds for the Central Universities SCU2025J4183Key Laboratory of the Evaluation and Monitoring of Southwest Land Resources (Ministry of Education) TDSYS202414National Natural Science Foundation of China 52203013Sichuan Science and Technology Program 2024NSFSC1030
6 · The paper itself

Abstract

Effective repair of vaginal defects, including those associated with Mayer-Rokitansky-Küster-Hauser syndrome, requires biomaterials that combine tissue-mimetic softness, hydration, mechanical resilience, and therapeutic activity. Here, we report a 3D-printable multifunctional hydrogel scaffold enabled by tetrahydroxy diboron (THDB) chemistry for accelerated vaginal defect repair. THDB triggers rapid radical polymerization of 2-hydroxyethyl methacrylate under oxygen-rich conditions, forming a poly(2-hydroxyethyl methacrylate) network strengthened by hydrogen bonding and B─O coordination from multiple boron species. The incorporation of calcium ions (Ca

Indexed as

Biocompatible MaterialsHydrogelsPrinting, Three-DimensionalTissue ScaffoldsVaginaAnimalsFemaleReactive Oxygen SpeciesTensile StrengthBiocompatible MaterialsHydrogelsReactive Oxygen Species3D‐printable tough hydrogel scaffolddynamic covalent–coordinative networkfull‐thickness vaginal defect repairreactive oxygen species‐scavenging hydrogeltetrahydroxydiboron‐enabled multifunctionality

Identifiers

PMID42260697
PMCPMC13356517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.