Evidence map›Paper›PMID 42260694›Full record

ArticleBMC global and public health2026

Yellow fever outbreak potential in Djibouti, Somalia and Yemen: a mathematical modelling study.

Keith Fraser, Laurence Cibrelus, Jennifer Horton, Chiori Kodama, J Erin Staples, Katy A M Gaythorpe

Abstract read
In one paragraph

Article in BMC global and public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Keith FraserMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, Wood Lane, London, United Kingdom.
Laurence CibrelusWorld Health Organization, Avenue Appia 20, 1211, Geneva, Switzerland.
Jennifer HortonWorld Health Organization, Avenue Appia 20, 1211, Geneva, Switzerland.
Chiori KodamaWorld Health Organization, Avenue Appia 20, 1211, Geneva, Switzerland.
J Erin StaplesDivision of Vector-borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA.
Katy A M GaythorpeMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, Wood Lane, London, United Kingdom. k.gaythorpe@imperial.ac.uk.

Funding

Bill and Melinda Gates Foundation INV-034281GAVI Alliance INV-034281Medical Research Council MR/X020258/1Wellcome Trust 226727 Z 22 Z
6 · The paper itself

Abstract

backgroundThe importation of arbovirus diseases into new countries is a global concern. This risk is exacerbated by human movement and climate change effects. In the World Health Organization (WHO) Eastern Mediterranean regional office, three countries - Djibouti, Somalia, and Yemen - are currently classified as potential or moderate risk for yellow fever (YF) outbreaks.

methodsHere we present a quantitative assessment of the risk of introduction and propagation of yellow fever virus (YFV) transmission in Djibouti, Somalia and Yemen. This modelling has two components: i) projecting the risk of importation of infectious individuals into the countries of interest using a radiation model of human movement and ii) estimating the risk of onward transmission given importation using a dynamic compartmental model of yellow fever virus transmission. Both components are multiplicatively combined to give an overall relative outbreak risk combining both risk of importation and risk of an outbreak given importation.

resultsWe show that areas such as the western coast of Yemen, regions of Somalia bordering Ethiopia and Kenya, and Djibouti City have potential for YF outbreaks (where the estimated probability of an outbreak given an imported infectious case is over 50%). This is due to environmental suitability for transmission based on factors such as temperature and projected human mobility between endemic and at-risk regions.

conclusionsCountries bordering existing YF endemic regions are potentially vulnerable to both introduction of YF cases and subsequent outbreak spread. This promotes the awareness of YF importation potential when conducting clinical surveillance in at-risk countries.

Indexed as

Mathematical modellingOutbreakTransmission riskYellow fever

Identifiers

PMID42260694
PMCPMC13245028

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.