Evidence map›Paper›PMID 42260659›Full record

ArticleParasites & vectors2026

Acaricidal efficacy and biochemical effects of Cananga odorata essential oil and three selected compounds against Haemaphysalis doenitzi (Acari: Ixodidae).

Songbo Zhang, Zhihua Gao, Boyu Yang, Xintong Liu, Chenxiao Lu, Haokun Feng, Pengxu Zhu, Zihan Liang, Ahmed H Ghonaim, Xiaolong Yang

Abstract read
In one paragraph

Article in Parasites & vectors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Songbo Zhang *Hebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, Hebei Collaborative Innovation Center for Eco-Environment, Ministry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China.
Zhihua Gao *Hebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, Hebei Collaborative Innovation Center for Eco-Environment, Ministry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China.
Boyu Yang *Hebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, Hebei Collaborative Innovation Center for Eco-Environment, Ministry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China.
Xintong LiuHebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, Hebei Collaborative Innovation Center for Eco-Environment, Ministry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China.
Chenxiao LuHebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, Hebei Collaborative Innovation Center for Eco-Environment, Ministry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China.
Haokun FengHebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, Hebei Collaborative Innovation Center for Eco-Environment, Ministry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China.
Pengxu ZhuHebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, Hebei Collaborative Innovation Center for Eco-Environment, Ministry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China.
Zihan LiangHebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, Hebei Collaborative Innovation Center for Eco-Environment, Ministry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China.
Ahmed H GhonaimNational Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Xiaolong YangHebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, Hebei Collaborative Innovation Center for Eco-Environment, Ministry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China. yangxl@hebtu.edu.cn.

Funding

Foundation of Hebei Normal University L2023B56Hebei Province Doctoral Candidate Innovation Capacity Development Grant Program CXZZBS2026085National Natural Science Foundation of China 31472050Natural Science Foundation of Hebei Province C2023205011
6 · The paper itself

Abstract

backgroundTicks are major ectoparasites that significantly impact livestock productivity worldwide. With the growing resistance to synthetic acaricides and increasing concerns about environmental and human safety, identifying effective and ecofriendly alternatives has become a pressing need. This study evaluated the fumigant and contact toxicities of ylang-ylang (Cananga odorata) essential oil (EO) and three plant-derived compounds, lilial, cinene, and α-amylcinnamaldehyde, against Haemaphysalis doenitzi and explored their underlying mechanisms of action.

methodsThe acaricidal potential of C. odorata EO, lilial, cinene, and α-amylcinnamaldehyde against H. doenitzi was evaluated through in vitro (fumigation and immersion tests) and subsequent biochemical effects experiments. Surviving adult ticks treated with the semi-lethal concentration (LC

resultsIn the fumigation assay, C. odorata EO and lilial showed the highest activity with the lowest LC

conclusionsCananga odorata EO, cinene, lilial, and α-amylcinnamaldehyde potently exhibit acaricidal activity via distinct but complementary disruption of detox enzymes, neurotransmission, and efflux pumps, offering a basis for novel plant-derived acaricides.

Indexed as

AcaricidesCanangaIxodidaeOils, VolatileAnimalsPlant OilsAcaricidesOils, VolatilePlant OilsAcaricidal activityBioactivityCananga odorata essential oilCineneLilialα-Amylcinnamaldehyde

Identifiers

PMID42260659
PMCPMC13343663

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.