Evidence map›Paper›PMID 42260498›Full record

ArticleBMC oral health2026

Efficacy of combined oral hygiene devices for interproximal plaque removal: an in vitro study.

Ryoko Otsuka, Ayako Okada, Nao Suzuki, Masahiro Nakano, Hiromi Uematsu, Toyotaro Sugawara, Emi Ishiguro, Nobuhiro Hanada, Yasuko Momoi, Chikahiro Ohkubo

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ryoko OtsukaDepartment of Oral Rehabilitation and Prosthodontics, Tsurumi University School of Dental Medicine, Yokohama, Japan.
Ayako OkadaDepartment of Preventive and Public Health Dentistry, Fukuoka Dental College, 2-15-1, Tamura, Sawara-ku, Fukuoka, 814-0193, Japan. okadaa@fdcnet.ac.jp.
Nao SuzukiDepartment of Preventive and Public Health Dentistry, Fukuoka Dental College, 2-15-1, Tamura, Sawara-ku, Fukuoka, 814-0193, Japan.
Masahiro NakanoNakano Dental Clinic, Ota, Japan.
Hiromi UematsuDivision of Dental Hygiene, The Nippon Dental University Hospital, Chiyoda, Japan.
Toyotaro SugawaraDepartment of Oral Rehabilitation and Prosthodontics, Tsurumi University School of Dental Medicine, Yokohama, Japan.
Emi IshiguroIshiguro Dental Clinic, Ichikawa, Japan.
Nobuhiro HanadaTsurumi University, Yokohama, Japan.
Yasuko MomoiTsurumi University, Yokohama, Japan.
Chikahiro OhkuboDepartment of Oral Rehabilitation and Prosthodontics, Tsurumi University School of Dental Medicine, Yokohama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study compared interproximal plaque removal rates when oral hygiene devices were used with a manual toothbrush.

methodsArtificial plaque was applied to the mesial interproximal surface of a lower left first molar mounted on a jaw model within a simulator. Removal was compared among 10 groups, including toothbrush alone (TB) and combinations of single-tufted brushes (Tuft), interdental brushes (IDB), and dental floss (string floss [SF] or holder-type floss [HF]). Five dental professionals performed the procedures. Pre- and post-cleaning images were analyzed to determine removal rates. Statistical analysis was conducted using a linear mixed-effects model with Tukey's post-hoc test.

resultsThe estimated marginal mean (EMM) for the TB group was 0.44 (95% confidence interval [CI]: 0.37-0.50). All combinations achieved significantly higher removal rates (p < 0.001). The TB, IDB, and SF combination achieved the highest EMM (0.93; 95% CI: 0.87-0.99). No significant differences were observed among the three SF combinations; however, all three demonstrated significantly higher rates than other protocols (p < 0.001).

conclusionsAdjunctive devices significantly improve interproximal plaque control compared to toothbrushing alone. Under the conditions of this experimental model, the combinations that included string floss demonstrated the highest efficacy for physical plaque removal. Further studies are needed in different anatomical settings and broader user populations.

Indexed as

Dental Devices, Home CareDental PlaqueOral HygieneToothbrushingHumansIn Vitro TechniquesDental flossInterdental brushPlaque removalSingle-tufted brush

Identifiers

PMID42260498
PMCPMC13466033

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.