ArticleBMC infectious diseases2026
Epidemiological characteristics of varicella in Xuzhou from 2015 to 2024: surveillance study.
Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundVaricella remains a major public health challenge in China, with limited evidence on long-term urban-rural epidemiological trends. This study analyzes varicella characteristics in Xuzhou, Jiangsu, 2015-2024, focusing on incidence, seasonality, and public health emergency events (PHEEs).
methodsThis surveillance study analyzed population-based varicella case data and public health emergency events (PHEEs) in Xuzhou City, China, from January 2015 to December 2024. Data were extracted from the China Disease Prevention and Control Information System and the National Notifiable Disease Reporting System. Varicella PHEEs were defined as ≥ 10 cases occurring in a collective unit within one week. We employed descriptive statistics, chi-square tests, and chi-square trend tests (for temporal trends of incidence rates) to analyze temporal trends and demographic distribution; the Mann-Kendall trend test was used to assess trends in PHEE-related indicators (duration, reporting latency, and case counts per event).
resultsAnnual incidence increased sharply to a peak of 65.01 per 100,000 in 2019, decreased in 2020, transiently rebounded in 2021, and then showed an overall declining pattern through 2024; overall, annual incidence varied significantly over the 10-year period (trend χ
conclusionsXuzhou's varicella epidemiology features seasonal clustering, age-specific vulnerability, and school-associated outbreaks. Strengthening rural/childhood vaccination and improving school PHEE responses are critical for control. CLINICAL TRIAL NUMBER: Not applicable.
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