ArticleBMC anesthesiology2026
Spinal cord-like hypertension syndrome with metabolic acidosis and pulmonary edema following lumbar discectomy under general anesthesia: a case report.
Article in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPercutaneous endoscopic lumbar discectomy (PELD) is a widely used minimally invasive spinal procedure. Rare but life-threatening complications related to irrigation-induced intraspinal hypertension have been reported, but cases under general anesthesia combined with metabolic acidosis and acute pulmonary edema are extremely rare and easily misdiagnosed. This case highlights a rare fatal complication and its clinical features to improve perioperative recognition and management. CASE PRESENTATION: A 56-year-old ASA II woman without hypertension or heart disease underwent elective PELD for L5-S1 disc herniation. Intraoperatively, persistent tachycardia and hypertension occurred despite adequate anesthesia depth. Postoperatively, she developed agitation, severe lactic acidosis, acute pulmonary edema, and required re-intubation and ICU treatment, complicated by stress cardiomyopathy. After systematic supportive therapy, she recovered and was discharged on postoperative day 12, with no sequelae at 1-month follow-up.
conclusionsSpinal cord-like hypertension syndrome is a rare but catastrophic complication of PELD, especially under general anesthesia. Early warning signs include unexplained intraoperative tachycardia and hypertension. Perioperative strategies such as reducing irrigation volume/pressure, close surgeon-anesthesiologist communication, and early intervention can improve patient safety and prognosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.