Evidence map›Paper›PMID 42260191›Full record

ArticlePflugers Archiv : European journal of physiology2026

Renal NHE3 is required to limit hypokalemia and metabolic acidosis during dietary potassium deficiency.

Jennifer Nogueira Coelho, Natalie Hayslip, Rebecca Zoe Halter, Sima Al-Masri, Adriana C C Girardi, Maryam Tahmasbi, Jessica A Dominguez Rieg, Timo Rieg

Abstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jennifer Nogueira Coelho *Morsani College of Medicine, Department of Molecular Pharmacology and Physiology, University of South Florida, 12901 Bruce B. Downs Blvd., Tampa, FL, 33612, USA.
Natalie Hayslip *Morsani College of Medicine, Department of Molecular Pharmacology and Physiology, University of South Florida, 12901 Bruce B. Downs Blvd., Tampa, FL, 33612, USA.
Rebecca Zoe HalterMorsani College of Medicine, Department of Molecular Pharmacology and Physiology, University of South Florida, 12901 Bruce B. Downs Blvd., Tampa, FL, 33612, USA.
Sima Al-MasriMorsani College of Medicine, Department of Molecular Pharmacology and Physiology, University of South Florida, 12901 Bruce B. Downs Blvd., Tampa, FL, 33612, USA.
Adriana C C GirardiLaboratório de Fisiologia Renal e Cardiometabolismo, Departamento de Cardiopneumologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Maryam TahmasbiJames A. Haley Veterans' Hospital, Tampa, FL, USA.
Jessica A Dominguez RiegMorsani College of Medicine, Department of Molecular Pharmacology and Physiology, University of South Florida, 12901 Bruce B. Downs Blvd., Tampa, FL, 33612, USA.
Timo RiegMorsani College of Medicine, Department of Molecular Pharmacology and Physiology, University of South Florida, 12901 Bruce B. Downs Blvd., Tampa, FL, 33612, USA. trieg@usf.edu.

Funding

Research and Education in Nephrology for Undergraduate Medical Students-Florida (RENUM-FL)R25DK134324 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI Jessica A Dominguez Rieg, Timo Rieg · 2024 to 2026
$323k
BLRD VA I01 BX004968NIDDK NIH HHS R25 DK134324NIDDK NIH HHS R25DK134324São Paulo State Research Foundation FAPESP 2021/14534-3U.S. Department of Veterans Affairs IBX004968A
6 · The paper itself

Abstract

The sodium-hydrogen exchanger isoform 3 (NHE3) is a critical mediator of proximal tubule and thick ascending limb Na

Indexed as

AcidosisHypokalemiaKidneyPotassium DeficiencyPotassium, DietarySodium-Hydrogen Exchanger 3AnimalsMaleMiceMice, Inbred C57BLMice, KnockoutPotassiumPotassiumPotassium, DietarySlc9a3 protein, mouseSodium-Hydrogen Exchanger 3

Identifiers

PMID42260191
PMCPMC13246878

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.