Evidence map›Paper›PMID 42260163›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2026

Response shift-adjusted longitudinal assessment of patient-reported outcomes in older people living with HIV: a multilevel structural equation and Rasch analysis.

Renjun Gu, Jia Li, Lei Jin, Taoying Zhu, Zongxing Yang, Xinhui Xu, Yuyuan Zhong, Jing Hu, Yiqing Weng, Fan Zhang and 11 more

Abstract read
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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

21 authors.

Renjun GuDepartment of Social Medicine of School of Public Health, Department of Pharmacy of the First Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China.
Jia LiDepartment of Social Medicine of School of Public Health, Department of Pharmacy of the First Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China.
Lei JinWuhou District Center for Disease Control and Prevention, 818 XingShi Road, Chengdu, 610041, Sichuan, China.
Taoying ZhuWuhou District Center for Disease Control and Prevention, 818 XingShi Road, Chengdu, 610041, Sichuan, China.
Zongxing YangSecond Department of Infectious Disease, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, 310023, China.
Xinhui XuDepartment of Social Medicine of School of Public Health, Department of Pharmacy of the First Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China.
Yuyuan ZhongDepartment of Social Medicine of School of Public Health, Department of Pharmacy of the First Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China.
Jing HuDepartment of Social Medicine of School of Public Health, Department of Pharmacy of the First Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China.
Yiqing WengDepartment of Social Medicine of School of Public Health, Department of Pharmacy of the First Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China.
Fan ZhangWuhou District Center for Disease Control and Prevention, 818 XingShi Road, Chengdu, 610041, Sichuan, China.
Guiying CaoDepartment of Infection and Immunology, The First Hospital of Changsha City (Changsha Hospital Affiliated to Xiangya Medical College, Central South University, Changsha, 410011, China.
Jianping XieDepartment of Infection and Immunology, The First Hospital of Changsha City (Changsha Hospital Affiliated to Xiangya Medical College, Central South University, Changsha, 410011, China.
Huayu LiDepartment of Social Medicine of School of Public Health, Department of Pharmacy of the First Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China.
Yu FuDepartment of Social Medicine of School of Public Health, Department of Pharmacy of the First Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China.
Dan LuoXiangya School of Public Health, Central South University, Changsha, China.
Shujuan YangWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Jinchuan ShiSecond Department of Infectious Disease, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, 310023, China.
Min WangDepartment of Infection and Immunology, The First Hospital of Changsha City (Changsha Hospital Affiliated to Xiangya Medical College, Central South University, Changsha, 410011, China.
Dongsheng HongDepartment of Social Medicine of School of Public Health, Department of Pharmacy of the First Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China.
Zhong ChenDepartment of Infection and Immunology, The First Hospital of Changsha City (Changsha Hospital Affiliated to Xiangya Medical College, Central South University, Changsha, 410011, China. chenzhong033@163.com.
Hongmei WangDepartment of Social Medicine of School of Public Health, Department of Pharmacy of the First Affiliated Hospital, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China. rosa@zju.edu.cn.

Funding

National Natural Science Foundation of China 72174177
6 · The paper itself

Abstract

purposeTo investigate the presence and clinical impact of response shift (RS) on longitudinal patient-reported outcome (PRO) assessment among older people living with HIV/AIDS (PLWHA), and to evaluate how not accounting for RS may affect the interpretation of changes in PRO at both domain and item levels.

methodsA two-wave longitudinal survey with a 3-month interval was conducted among older PLWHA (baseline n = 1245; follow-up rate 84.90%) using the PROHIV-OLD instrument. Domain-level RS-including reconceptualization, recalibration, and reprioritization-was examined using Oort's structural equation modeling (SEM) approach. Item-level recalibration was further assessed within the Mental Status domain using the updated ROSALI-Rasch measurement theory (RMT) algorithm, incorporating clinical subgroups defined by diagnostic duration, disease stage, and HIV-1 RNA status.

resultsAt the domain level, a medium uniform recalibration was detected for Physical Symptoms (Est. = 0.65, Δχ

conclusionRS substantially informs longitudinal PRO assessment in older PLWHA. Accounting for RS effects can improve the interpretation of changes in PROs and support more patient-centered clinical evaluation in aging HIV populations.

Indexed as

HIV InfectionsPatient Reported Outcome MeasuresQuality of LifeAgedFemaleHumansLatent Class AnalysisLongitudinal StudiesMaleMiddle AgedPsychometricsSurveys and QuestionnairesOlder people living with HIV/AIDSPatient-reported outcomesResponse shiftROSALIStructural equation model

Identifiers

PMID42260163

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.