ReviewOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026
Association between vestibular dysfunction and osteoporosis in adults: a systematic review and meta-analysis.
Review in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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15 authors.
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Abstract
Multiple clinical studies have demonstrated that vestibular dysfunctions, such as benign paroxysmal positional vertigo (BPPV) and Meniere's disease (MD), are associated with osteoporosis or osteopenia in adults. Animal studies have also indicated that selective ablation of peripheral vestibular organs leads to reduced bone mineral density in mice, potentially through effects on the sympathetic nervous system. This review systematically evaluates the association between vestibular dysfunction and osteoporosis in adults and reports the prevalence of this comorbidity. We systematically searched PubMed, MEDLINE, EMBASE, the Cochrane Library, Scopus, and Web of Science databases for studies published from January 2000 to December 2025. Two authors independently screened and extracted data. Meta-analyses were performed to compare vestibular function test results between adults with and without osteoporosis and to compare the morbidity of osteoporosis between individuals with and without vestibular dysfunction. A total of 33 studies were included. Among these, 21 case-control studies examined the risk of osteoporosis in adults with vestibular dysfunction, and the remaining cross-sectional/prospective studies reported its prevalence. Findings are presented in four sections. (1) Risk of vestibular dysfunction: osteoporosis vs non-osteoporosis controls: due to moderate heterogeneity persisting after sensitivity analysis (I
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