Development of a pH-responsive starch-based nanocarrier polyacrylic acid containing SiO

Mehrab Pourmadadi, Pegah Poorkhalili, Maryam Hosseini, Samira Piran, Amir Reza Hafezi, Abdullah Kamaluldeen, Mohammad Najafi, Tahmineh Ahmadi

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Mehrab PourmadadiProtein Research Center, Shahid Beheshti University, Tehran, Tehran, GC, 1983963113, Iran. mehrabpourmadadi@gmail.com.

Pegah PoorkhaliliSchools of Life Science Engineering, College of Interdisciplinary Science and Technology, University of Tehran, Tehran, Iran.

Maryam HosseiniSchool of Chemical Engineering, College of Engineering, University of Tehran, P.O. Box 11155/4563, Tehran, Iran.

Samira PiranDepartment of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran.

Amir Reza HafeziDepartment of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran.

Abdullah KamaluldeenBiomedical Engineering Department, College of Engineering, Al-Mustaqbal University, Hillah, Babil, 51001, Iraq.

Mohammad NajafiDepartment of Chemistry, Amirkabir University of Technology, Tehran, 1591634311, Iran.

Tahmineh AhmadiDepartment of Biomedical Engineering, CT.C., Islamic Azad University, P.O. Box 13185/768, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is still a major worldwide health concern, and traditional treatment methods can have serious side effects. In order to improve the therapeutic use of quercetin (QC) in the treatment of cancer, this work presents a newly developed pH-responsive nanocomposite. The water-in-oil-in-water (W/O/W) double emulsion approach was used to create the nanocarrier, which is an effective QC delivery system made up of silica nanoparticles (SiO

Indexed as

Acrylic ResinsDrug CarriersNanoparticlesQuercetinSilicon DioxideStarchCell SurvivalDelayed-Action PreparationsDrug LiberationHumansHydrogen-Ion ConcentrationParticle SizeAcrylic Resinscarbopol 940Delayed-Action PreparationsDrug CarriersQuercetinSilicon DioxideStarchColon cancerDrug delivery systempH-sensitive nanocarrierPolyacrylic acidQuercetinSilica nanoparticlesStarch

Identifiers

PMID42260091

DOI10.1038/s41598-026-57272-0

PMCPMC13486477

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.