Evidence map›Paper›PMID 42260063›Full record

ReviewAmerican journal of clinical dermatology2026

What's New in Photoprotection?

Zita Álvarez-Bobillo, Tamara Gracia-Cazaña, Yolanda Gilaberte, Henry W Lim

Abstract readReview
PubMed Publisher
In one paragraph

Review in American journal of clinical dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zita Álvarez-BobilloDermatology Service, Department of Dermatology, Miguel Servet University Hospital, IIS Aragón, Paseo Isabel la Católica 1-3, P.O. Box: 50009, Zaragoza, Spain.ORCID http://orcid.org/0009-0003-6891-9718
Tamara Gracia-CazañaDermatology Service, Department of Dermatology, Miguel Servet University Hospital, IIS Aragón, Paseo Isabel la Católica 1-3, P.O. Box: 50009, Zaragoza, Spain.ORCID http://orcid.org/0000-0002-0523-2076
Yolanda GilaberteDermatology Service, Department of Dermatology, Miguel Servet University Hospital, IIS Aragón, Paseo Isabel la Católica 1-3, P.O. Box: 50009, Zaragoza, Spain. ygilaberte@gmail.com.ORCID http://orcid.org/0000-0001-8034-3617
Henry W LimDivision of Photobiology and Photomedicine, Department of Dermatology, Henry Ford Health, Detroit, MI, USA.ORCID http://orcid.org/0000-0002-1576-1115

Funding

Departamento de Educación, Cultura y Deporte, Gobierno de Aragón PhotobiologyDepartamento de Educación, Cultura y Deporte, Gobierno de Aragón Research group of Aragon Goverment B59_23D Dermatology
6 · The paper itself

Abstract

It is well established that a complete package of photoprotection includes staying in the shade, wearing photoprotective clothing, hat, and sunglasses, and on otherwise exposed sites, applying sunscreen. Recent advances have modified photoprotection through new active ingredients, innovative formulations, complementary oral strategies, and personalized approaches. This review aims to summarize the latest new developments in photoprotection. A narrative review of the literature was conducted from January 2010 to October 2025 using terms related to photoprotection, sunscreen innovation, visible light, oral photoprotection, microbiome interaction, climate change, and personalized approaches. Articles in English and Spanish were selected based on scientific relevance. Advances in photoprotection include the development of new topical filters targeting UVA1 and visible light, as well as the incorporation of iron oxides and, in some formulations, pigmentary titanium dioxide in tinted sunscreens to enhance protection against visible light. In addition, the use of antioxidants and DNA repair enzymes has been explored to mitigate oxidative stress and address field cancerization. Natural and eco-friendly bioactive ingredients derived from botanical and marine sources show growing potential as photoprotective agents. Additional considerations such as the role of skin microbiome, and personalized photoprotection strategies tailored to skin phototype, lifestyle, diseases, and high-exposure conditions further refine preventive practice. Photoprotection is evolving into a multidimensional approach that integrates advanced topical formulations, oral agents, and individualized recommendations. This paradigm offers improved prevention of photoaging, pigmentary disorders, and photocarcinogenesis while promoting safer and more sustainable photoprotection practices.

Indexed as

Skin NeoplasmsSunscreening AgentsAntioxidantsHumansSkinSkin MicrobiomeSunlightUltraviolet RaysAntioxidantsSunscreening Agents

Identifiers

PMID42260063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.