Evidence map›Paper›PMID 42259979›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2026

Exploring the medicinal potential of Bulbine latifolia (L.f.) Spreng.: a comprehensive review of phytochemicals and therapeutic applications.

Atif Ali Khan Khalil, Hanhong Bae

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Atif Ali Khan KhalilDepartment of Biotechnology, Yeungnam University, Gyeongsan, 38541, Republic of Korea. atif.ali@yu.ac.kr.
Hanhong BaeDepartment of Biotechnology, Yeungnam University, Gyeongsan, 38541, Republic of Korea. hanhongbae@ynu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bulbine latifolia (L.f.) Spreng. (syn. Bulbine natalensis), a succulent medicinal plant native to southern Africa and belonging to the family Asphodelaceae, has attracted considerable attention due to its ethnomedicinal significance and pharmacological potential. Traditionally used for the treatment of wounds, skin disorders, infections, and metabolic conditions, this species is recognized for its diverse therapeutic applications in indigenous healthcare systems. Phytochemical investigations have revealed a wide range of bioactive constituents, including anthraquinones, triterpenes, sterols, fatty acids, and phenolic compounds. Recent studies have demonstrated its stimulant, antioxidant, anti-inflammatory, antimicrobial, antidiabetic, wound-healing, and apoptotic activities, supporting its relevance in both traditional and modern medicine. These bioactive compounds are known to modulate key biological pathways associated with oxidative stress, inflammation, and hormonal regulation. This review aims to provide a comprehensive and updated overview of B. latifolia, highlighting its phytochemical diversity, pharmacological properties, and underlying mechanisms of action, as well as its potential for future drug development.

Indexed as

AsphodelaceaePhytochemicalsPlant ExtractsAnimalsHumansPhytotherapyPlants, MedicinalPhytochemicalsPlant ExtractsBulbineBulbine latifoliaMedicinal plantPharmacologicalPhytochemical

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.