ArticleNature2026
GPR15-guided CD8
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
67 authors.
Jing Cui *Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Zuojia Chen *Experimental Immunology Branch, National Cancer Institute (NCI), NIH, Bethesda, MD, USA.
Yan H ChengMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Jia NieLaboratory of Immune Cell Biology and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.
Maria H ZhuMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-7347-2143
Chen XiangMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-1072-6230
Samuel ChauvinPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-0232-751X
Wiem LassouedCenter for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.
Can LiuMultiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-8411-3891
Kartika PadhanLaboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-9561-4256
Jian SongLaboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.
Joy A PaiCalico Life Sciences, South San Francisco, CA, USA.
Borja OcónLaboratory of Immunology and Vascular Biology, Department of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-5136-7844
Yifan YangDivision of Intramural Research, National Library of Medicine, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-4414-9176
Yikun YaoMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Ann Y ParkMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-0130-1521
Justin Q GabrielskiMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-2953-2874
Lixin ZhengMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Ping Du JiangMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Yu ZhangClinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.
Huie JingClinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.
Leilei XuMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Vicky ChenIntegrated Data Sciences Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-4595-154X
Brent A CalabresiTranslational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA.
Stefania PittalugaLaboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-7688-1439
David E KleinerLaboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-3442-4453
Clifton L DalgardDepartment of Anatomy, Physiology and Genetics, Uniformed Services University, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-2025-8239
Sinan SariDepartment of Pediatric Gastroenterology, Gazi University Faculty of Medicine, Ankara, Türkiye.ORCID http://orcid.org/0000-0002-6316-4593
Salim CanDepartment of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.ORCID http://orcid.org/0000-0003-3797-3001
Elif Karakoc-AydinerDepartment of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.ORCID http://orcid.org/0000-0003-4150-5200
Safa BarisDepartment of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.ORCID http://orcid.org/0000-0002-4730-9422
Baran ErmanInstitute of Child Health, Can Sucak Research Laboratory for Translational Immunology, Hacettepe University, Ankara, Türkiye.
Michael FieldDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-4003-0568
Jocelyn A SilvesterDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Gwen SaccociaDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Eman K BuhamrahPediatric Gastroenterology and Hepatology Department, Al-Amiri Hospital, Kuwait City, Kuwait.
Khaled HusainPediatric Gastroenterology, Hepatology and Nutrition Department, Dar Al Shifa Hospital, Kuwait City, Kuwait.
Zahra ChavoshzadehAllergy and Clinical Immunology Department, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nima RezaeiResearch Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-3836-1827
Ali İşlekCukurova University Faculty of Medicine, Department of Pediatrics, Division of Gastroenterology and Hepatology, Adana, Türkiye.ORCID http://orcid.org/0000-0001-6172-7797
Hasan BaşIntergen Genetics and Rare Diseases Diagnosis Center, Ankara, Türkiye.ORCID http://orcid.org/0000-0003-3475-564X
Fatma Dereli DevrezIntergen Genetics and Rare Diseases Diagnosis Center, Ankara, Türkiye.
Rafah MackehTranslational Medicine Department, Research Department, Sidra Medicine, Doha, Qatar.ORCID http://orcid.org/0000-0003-3648-2198
Ivan J FussMucosal Immunity Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.
Daniel S ReichTranslational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-2628-4334
Shania BaileyCenter for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.
Houssein Abdul SaterCenter for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.
James L GulleyCenter for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-6569-2912
Juraj KabatBiological Imaging Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.
Margery SmelkinsonBiological Imaging Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-7777-5574
Sundar GanesanBiological Imaging Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.
Zhenghao ChenCalico Life Sciences, South San Francisco, CA, USA.
Peter C GraysonVasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal, and Skin Diseases, NIH, Bethesda, MD, USA.
Neelam RedekarIntegrated Data Sciences Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-4819-9034
Justin LackIntegrated Data Sciences Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.
Zhiyong LuDivision of Intramural Research, National Library of Medicine, NIH, Bethesda, MD, USA.
Bernice LoTranslational Medicine Department, Research Department, Sidra Medicine, Doha, Qatar.
Hassan AbolhassaniResearch Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-4838-0407
Ahmet OzenDepartment of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.ORCID http://orcid.org/0000-0002-9065-1901
Athos BousvarosDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Scott B SnapperDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0267-4247
Eugene C ButcherLaboratory of Immunology and Vascular Biology, Department of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-8786-7907
Juan RavellDivision of Allergy and Immunology, Department of Internal Medicine, Hackensack University Medical Center, Hackensack, NJ, USA.ORCID http://orcid.org/0000-0001-6687-2555
Rémy BosselutLaboratory of Immune Cell Biology and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.
Helen C SuMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-5582-9110
Chuan WuExperimental Immunology Branch, National Cancer Institute (NCI), NIH, Bethesda, MD, USA. chuan.wu@nih.gov.ORCID http://orcid.org/0000-0003-2288-353X
Michael J LenardoMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA. lenardo@calicolabs.com.ORCID http://orcid.org/0000-0003-1584-468X
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammatory bowel disease (IBD) causes chronic suffering from gastrointestinal inflammation and dysfunction that can progress to colon cancer
Indexed as
CD8-Positive T-LymphocytesInflammatory Bowel DiseasesIntestinesReceptors, G-Protein-CoupledReceptors, PeptideT-Lymphocytes, RegulatoryAnimalsColitisColonFas Ligand ProteinFemaleHumansInflammationIntestinal MucosaMacrophagesMaleFas Ligand ProteinGPR15 protein, humanGpr15 protein, mouseReceptors, G-Protein-CoupledReceptors, Peptide
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.