Evidence map›Paper›PMID 42259659›Full record

ArticleBritish journal of haematology2026

Improved real-world outcomes of patients with acute promyelocytic leukaemia treated with first-line arsenic trioxide in specialized centres in Portugal through a 24/7 phone-based referral.

Joana Brioso Infante, Eliana Aguiar, Inês Sá, Inês Marques, Miguel Neto, Cátia Almeida, Telma Nascimento, Marta Pereira, Emília Cortesão, Guilherme Sapinho and 9 more

Abstract read
In one paragraph

Article in British journal of haematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Predictors of Early Death in Acute Promyelocytic Leukemia.Medical sciences (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Joana Brioso InfanteDepartment of Haematology and Marrow Transplantation, Unidade Local de Saúde de Santa Maria, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-4505-2299
Eliana AguiarDepartment of Haematology, Unidade Local de Saúde de São João, Porto, Portugal.
Inês SáDepartment of Haematology, Unidade Local de Saúde de São João, Porto, Portugal.
Inês MarquesDepartment of Haematology, Unidade Local de Saúde de São João, Porto, Portugal.
Miguel NetoDepartment of Haematology, Unidade Local de Saúde de São João, Porto, Portugal.
Cátia AlmeidaDepartment of Haematology, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.
Telma NascimentoDepartment of Haematology, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.
Marta PereiraDepartment of Haematology, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.
Emília CortesãoDepartment of Haematology, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.
Guilherme SapinhoDepartment of Haematology and Marrow Transplantation, Unidade Local de Saúde de Santa Maria, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-6576-631X
Graça EstevesDepartment of Haematology and Marrow Transplantation, Unidade Local de Saúde de Santa Maria, Lisbon, Portugal.
Tiago Monteiro-BrásDepartment of Haematology, Unidade Local de Saúde de Santo António, Porto, Portugal.
Luísa RegadasDepartment of Haematology, Unidade Local de Saúde de Santo António, Porto, Portugal.
Inês VieiraDepartment of Haematology, Unidade Local de Saúde de São José, Lisbon, Portugal.
Filipa SaraivaDepartment of Haematology, Unidade Local de Saúde de São José, Lisbon, Portugal.
Georgy AlikhanovDepartment of Haematology, Unidade Local de Saúde de São José, Lisbon, Portugal.
Joana SantosDepartment of Haematology, Unidade Local de Saúde de São José, Lisbon, Portugal.
Patrícia RibeiroDepartment of Haematology, Unidade Local de Saúde de São José, Lisbon, Portugal.
Fernanda TrigoDepartment of Haematology, Unidade Local de Saúde de São João, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 24/7 phone-based referral system allows for the fast transfer of acute promyelocytic leukaemia (APL) patients to select sites specialized in APL in Portugal. A reduction in the early death (ED) rate from 11.4% in non-high-risk patients to 3.7% in this cohort and universal complete response (CR) plus measurable residual disease (MRD) negativity were achieved with frontline arsenic trioxide (ATO) in APL.

Indexed as

Antineoplastic AgentsArsenic TrioxideLeukemia, Promyelocytic, AcuteReferral and ConsultationAdultAgedFemaleHumansMaleMiddle AgedPortugalTelephoneTreatment OutcomeYoung AdultAntineoplastic AgentsArsenic Trioxideacute promyelocytic leukaemiaall‐trans retinoic acidarsenic trioxideearly deathreal‐world outcomes

Identifiers

PMID42259659
PMCPMC13462206

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.