Evidence map›Paper›PMID 42259587›Full record

ArticleJournal of the American Chemical Society2026

Development of a Nucleoside Photosensitizer Efficiently Activated by One- or Two-Photon Absorption in the Optical Therapeutic Window.

Sourav Kanti Seth, Sean J Hoehn, Chris Acquah, Liraz Levi, Carlos E Crespo-Hernández

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sourav Kanti SethDepartment of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States.ORCID 0000-0002-6001-2156
Sean J HoehnDepartment of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States.ORCID 0000-0002-8282-7807
Chris AcquahDepartment of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Liraz LeviDepartment of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, United States.
Carlos E Crespo-HernándezDepartment of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States.ORCID 0000-0002-3594-0890

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing DNA/RNA nucleoside prodrugs that absorb in the red-to-near-infrared is crucial for applications requiring deep-tissue penetration. This study reports the rational design and synthesis of a novel thiocarbonyl analog, 5-(5-(4-(dimethylamino)phenyl)thiophen-2-yl)-2',3',5'-tri-

Indexed as

Antineoplastic AgentsNucleosidesPhotonsPhotosensitizing AgentsAnimalsCell Line, TumorHumansMiceMolecular StructureAntineoplastic AgentsNucleosidesPhotosensitizing Agents

Identifiers

PMID42259587
PMCPMC13307366

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.