ArticleUltrasonics sonochemistry2026
Nanofiltration concentration process of Ganoderma lucidum glycopeptides and membrane fouling mechanism based on the ultrasonic-regulated adsorption and concentration kinetics.
Article in Ultrasonics sonochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Power Ultrasound as an Intensification Strategy in Food Biomanufacturing: Applications, Mechanisms and Perspectives.Foods (Basel, Switzerland) · 2026Review
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10 authors.
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Abstract
Lingzhi is the dried fruiting body of the fungus Ganoderma lucidum from the polyporaceae. It's non-toxic and has medicinal and edible use. The active ingredient Ganoderma lucidum glycopeptide presents a manufacturing problem of nanofiltration membrane contamination during concentration at room temperature because of its heat sensitivity. During the nanofiltration concentration process of Ganoderma lucidum glycopeptides, membrane fouling leads to low production efficiency, which is the primary problem limiting industrial production. In this study, a nanofiltration concentration model appropriate for industrial application has been developed and the nanofiltration contamination mechanism of Ganoderma lucidum glycopeptides was elucidated using ultrasound-assisted separation. Adsorption kinetics, concentration kinetics, and concentration polarization coefficient models were used to investigate the nanofiltration separation and contamination behavior of Ganoderma lucidum glycopeptides regulated by ultrasound. The nanofiltration contamination mechanism of Ganoderma lucidum glycopeptides was elucidated in conjunction with the membrane surface microstructure analysis. The ultrasonic-assisted membrane separation parameters were optimized to be transmembrane pressure 0.6 MPa, ultrasonic power 432 W, and pH 8.00, with rejections of triterpenoids, proteins, and sugars of 99.7%-94.4%, 97.8%-95.2%, and 91.8%-85.7%, respectively, as the fermentation broth volume increased from 2 L to 50 L. Accordingly, the SCQ-9200E ultrasonic apparatus has a bath tank, an ultrasonic frequency of 40 kHz, a power density of 0.24 W/cm
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