Evidence map›Paper›PMID 42258811›Full record

SynthesisJournal of medical Internet research2026

Artificial Intelligence Governance in Health Systems: Systematic Review of Frameworks and Integrative Model Proposal.

Hassane Alami, Renata Pozelli Sabio, Elsury Johanna Pérez, Marie-Pierre Gagnon, Lyse Langlois, Jean-Louis Denis, Kathy Malas, Lysanne Rivard, Mathilde Savoldelli, Mohamed Ali Ag Ahmed and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of medical Internet research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hassane AlamiDepartment of Health Management, Evaluation and Policy, School of Public Health & Center for Public Health Research of the University of Montreal, P.O. Box 6128, Branch Centre-Ville, Montreal, QC, H3C 3J7, Canada, 1 (514) 343-7978.ORCID http://orcid.org/0000-0002-5461-7693
Renata Pozelli SabioDepartment of Health Management, Evaluation and Policy, School of Public Health & Center for Public Health Research of the University of Montreal, P.O. Box 6128, Branch Centre-Ville, Montreal, QC, H3C 3J7, Canada, 1 (514) 343-7978.ORCID http://orcid.org/0000-0002-8189-1989
Elsury Johanna PérezDepartment of Health Management, Evaluation and Policy, School of Public Health & Center for Public Health Research of the University of Montreal, P.O. Box 6128, Branch Centre-Ville, Montreal, QC, H3C 3J7, Canada, 1 (514) 343-7978.ORCID http://orcid.org/0000-0001-8234-391X
Marie-Pierre GagnonFaculty of Nursing, Laval University, Quebec, QC, Canada.ORCID http://orcid.org/0000-0002-0782-5457
Lyse LangloisDepartment of Industrial Relations, Laval University, Quebec, QC, Canada.ORCID http://orcid.org/0000-0003-4774-9847
Jean-Louis DenisInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.ORCID http://orcid.org/0000-0003-1295-332X
Kathy MalasDepartment of Health Management, Evaluation and Policy, School of Public Health & Center for Public Health Research of the University of Montreal, P.O. Box 6128, Branch Centre-Ville, Montreal, QC, H3C 3J7, Canada, 1 (514) 343-7978.ORCID http://orcid.org/0000-0001-8419-0507
Lysanne RivardDepartment of Health Management, Evaluation and Policy, School of Public Health & Center for Public Health Research of the University of Montreal, P.O. Box 6128, Branch Centre-Ville, Montreal, QC, H3C 3J7, Canada, 1 (514) 343-7978.ORCID http://orcid.org/0000-0003-4650-2543
Mathilde SavoldelliDepartment of Health Management, Evaluation and Policy, School of Public Health & Center for Public Health Research of the University of Montreal, P.O. Box 6128, Branch Centre-Ville, Montreal, QC, H3C 3J7, Canada, 1 (514) 343-7978.ORCID http://orcid.org/0000-0003-2747-7936
Mohamed Ali Ag AhmedDepartment of Health Management, Evaluation and Policy, School of Public Health & Center for Public Health Research of the University of Montreal, P.O. Box 6128, Branch Centre-Ville, Montreal, QC, H3C 3J7, Canada, 1 (514) 343-7978.ORCID http://orcid.org/0000-0001-9374-871X
Jean-Paul FortinFaculty of Medicine, Laval University, Quebec, QC, Canada.ORCID http://orcid.org/0000-0002-4107-9937

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Several artificial intelligence (AI) governance frameworks have emerged to help health systems (HS) address AI-related risks. However, most fail to capture the multidimensional and evolving nature of real-world governance. Objective: This systematic review aimed to synthesize existing AI governance frameworks for HS and to propose an integrative AI governance model identifying key components to guide AI-related policy, practice, and research in HS. Methods: A comprehensive search was conducted in 8 academic databases (PubMed, MEDLINE, Embase, ACM Digital Library, Web of Science, Scopus, Social Sciences Abstracts, and PsycINFO), gray literature databases, and international organization web portals in October 2024 (updates: July 2025 and March 2026) and limited to studies published from November 2014 to March 2026 in English, French, Spanish, or Portuguese. Eligible documents included peer-reviewed articles and reports proposing AI governance frameworks for HS. Two reviewers independently selected the frameworks, assessed their quality using the Appraisal of Guidelines for Research and Evaluation for Health Systems, and extracted data. Results were synthesized using thematic analysis. Results: The research retrieved 10,175 records, among which 19 AI governance frameworks were identified. Most were published between 2022 and 2024 (n=13, 68%), half (n=10, 53%) were developed by authors based in North America, and only one-third (n=6, 32%) were derived from primary studies. The frameworks focused on 4 levels of AI governance: international (n=3, 16%), national (n=5, 26%), local (n=3, 16%), and organizational (n=8, 42%). All of them underline the crucial role of multidisciplinary bodies in the structure of AI governance in HS. Six key AI governance processes in HS emerged as critical: (1) need and/or problem identification (n=14, 74%), (2) data governance (n=17, 89%), (3) risk assessment and management (n=17, 89%), (4) validation and/or evaluation (n=18, 95%), (5) maintenance and monitoring (n=16, 84%), and (6) integration (n=9, 47%). Additionally, 4 pivotal relational mechanisms were identified: (1) ethical principles and/or values (n=17, 89%), (2) education and training (n=14, 74%), (3) communication (n=12, 63%), and (4) standards and regulations (n=13, 68%). Conclusions: Our study provides a comprehensive synthesis of existing AI governance frameworks for HS across 4 levels (local, regional, national, and international), underpinned by a quality assessment of the 19 identified frameworks. It differs from existing studies that concentrate on specific dimensions or settings by contributing an integrative AI governance model for HS comprising 2 dimensions and 4 relational mechanisms across the 4 levels, explicitly modeling their interactions. Future research should test and operationalize the proposed model to enhance its practical applicability. Strengthening the methodological rigor of AI governance frameworks will be essential for the responsible integration of AI in HS. As the framework is primarily grounded in Global North and English-language literature, validation in other contexts is warranted.

Indexed as

Artificial IntelligenceDelivery of Health CareHumansartificial intelligencedeep learningdigital healthgovernancehealth systemmachine learningnatural language processing

Identifiers

PMID42258811
PMCPMC13245845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.