Evidence map›Paper›PMID 42258713›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Active zone plasticity couples sleep need to presynaptic hypophosphorylation.

Chengji Piao, Ewelina P Dutkiewicz, Laxmikanth Kollipara, Albert Sickmann, Sheng Huang, Stephan J Sigrist

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chengji PiaoInstitute for Biology/Genetics, Freie Universität Berlin, Berlin 14195, Germany.ORCID 0000-0002-8753-2100
Ewelina P DutkiewiczLeibniz-Institut für Analytische Wissenschaften, Dortmund 44139, Germany.ORCID 0000-0002-8852-4188
Laxmikanth KolliparaLeibniz-Institut für Analytische Wissenschaften, Dortmund 44139, Germany.ORCID 0000-0002-2673-0488
Albert SickmannLeibniz-Institut für Analytische Wissenschaften, Dortmund 44139, Germany.
Sheng HuangInstitute for Biology/Genetics, Freie Universität Berlin, Berlin 14195, Germany.ORCID 0000-0003-3328-3142
Stephan J SigristInstitute for Biology/Genetics, Freie Universität Berlin, Berlin 14195, Germany.ORCID 0000-0002-1698-5815

Funding

Deutsche Forschungsgemeinschaft (DFG) 327654276EC | European Research Council (ERC) 101097053IPF | Leibniz-Gemeinschaft (LG) K169/2018
6 · The paper itself

Abstract

Sleep need is associated with both circuit dynamics and widespread synaptic plasticity, yet the specific synaptic changes underlying sleep homeostasis remain incompletely understood. In

Indexed as

Drosophila ProteinsNeuronal PlasticityPresynaptic TerminalsSleepAnimalsCyclic AMP-Dependent Protein KinasesDrosophila melanogasterMicrofilament ProteinsNerve Tissue ProteinsNeurabinsPhosphorylationProtein Phosphatase 1SynapsesBRP protein, DrosophilaCyclic AMP-Dependent Protein KinasesDrosophila ProteinsMicrofilament ProteinsNerve Tissue ProteinsNeurabinsProtein Phosphatase 1active zoneBruchpilot (BRP)phosphorylationsleep homeostasissynaptic plasticity

Identifiers

PMID42258713
PMCPMC13273273

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.