ArticlePloS one2026
Multidrug resistance and inappropriate empiric therapy as predictors of hospital stay in diabetic foot infections.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study explored the causative pathogens, resistance patterns, and treatment appropriateness for diabetic foot infections (DFI) at a tertiary care center in Jordan.
methodsA retrospective review was conducted on 234 patients diagnosed with DFIs at a tertiary care center in Jordan. Data collected included patient demographics, diabetes history, infection severity, culture results, and antibiotic treatment details. Bacterial isolates were classified as multidrug-resistant (MDR) or non-MDR based on standard definitions. Therapy was considered appropriate if at least one antibiotic given within the first 48 hours of admission covered all identified pathogens and was administered with the correct dosage, formulation, and route. Statistical analyses examined the relationship between resistance patterns, treatment adequacy, and hospital stay duration.
resultsThe most frequently isolated bacterium was Staphylococcus aureus, identified in 117 cases (50.0%), including MRSA (n = 46, 19.6%) and MSSA (n = 71, 30.3%). This was followed by Escherichia coli in 33 cases (14.1%) and Pseudomonas aeruginosa in 32 cases (13.7%). MDR organisms accounted for 152 infections (65%). Empiric therapy was deemed appropriate in 111 patients (47.4%), inappropriate in 74 (31.6%), and not assessable due to missing data in 49 (20.9%). Following culture and susceptibility results, antibiotics in 87 cases (37.2%) remained unchanged. In multivariate analysis, only infection severity was significantly associated with prolonged hospitalization (β = -0.161, P = 0.034).
conclusionMDR organisms were common in DFIs but not significantly associated with prolonged hospitalization. Infection severity was the key predictor of length of stay. These findings highlight the importance of early infection assessment, appropriate empirical therapy based on local resistance patterns, and robust antibiotic stewardship.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.