Evidence map›Paper›PMID 42258525›Full record

ArticlePLoS neglected tropical diseases2026

Discovery of a novel coltivirus in a newly identified Bat Bug Species (Heteroptera: Cimicidae) in Cambodia.

Jurre Y Siegers, Heidi Auerswald, Pierre-Olivier Maquart, Tamara Szentiványi, Julia Guillebaud, Thavry Hoem, Xiang Li, Kimhuor Suor, Leakhena Pum, Limmey Khun and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PLoS neglected tropical diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jurre Y SiegersVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Heidi AuerswaldVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Pierre-Olivier MaquartMedical and Veterinary entomology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Tamara SzentiványiHUN-REN Centre for Ecological Research, Institute of Ecology and Botany, Vácrátót, Hungary.
Julia GuillebaudVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Thavry HoemVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Xiang LiProgramme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore.
Kimhuor SuorMedical and Veterinary entomology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Leakhena PumVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Limmey KhunVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Sithun NuonVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Kimlay CheaVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Vireak HeangVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Kathrina Mae BienesVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Yvonne C F SuProgramme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore.
Veasna DuongVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Janin NouhinVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Sébastien BoyerMedical and Veterinary entomology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.
Erik A KarlssonVirology Unit, Institut Pasteur du Cambodge, Pasteur Network, Phnom Penh, Cambodia.ORCID https://orcid.org/0000-0001-6004-5671

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bats and their ectoparasites are significant reservoirs and potential vectors of emerging zoonotic pathogens, yet the viral diversity within bat-associated arthropods remains poorly characterized. This study reports the identification of a novel coltivirus (order Reovirales), provisionally designated Stricticimex coltivirus (SCCV), in a newly described bat bug species, Stricticimex phnomsampovensis, collected from cave-dwelling wrinkle-lipped free-tailed bats (Mops plicatus) in Cambodia. Metagenomic sequencing and phylogenetic analysis revealed that SCCV clusters within the Coltivirus genus, showing closest similarity to Tai Forest Reovirus (TFRV) previously isolated from African bats. SCCV was detected in 18.4% of examined bat bugs and successfully isolated in VeroE6 cells, with replication confirmed in multiple mammalian cell lines. The discovery of SCCV extends the known diversity and geographic range of coltiviruses and highlights bat ectoparasites as overlooked hosts of potentially zoonotic viruses. These findings underscore the importance of integrated One Health surveillance targeting both bats and their ectoparasites to better assess the risk of pathogen spillover in biodiverse regions with high human-animal contact.

Indexed as

ChiropteraColtivirusAnimalsCambodiaChlorocebus aethiopsGenome, ViralPhylogenyRNA, ViralSequence Analysis, DNAVero CellsRNA, Viral

Identifiers

PMID42258525
PMCPMC13258151

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.