Evidence map›Paper›PMID 42258483›Full record

ArticlePloS one2026

Pathogen spectrum and epidemiology of respiratory tract infections in Quzhou, Eastern China, from November 2023 to July 2024: A post‑COVID‑19 surveillance study.

Rui-Jun Yang, Min Wang, Lei Lyu, Jia-Ling You, Shi-Teng Huang, Bing-Dong Zhan

Abstract read
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Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Rui-Jun YangQuzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-8309-7375
Min WangQuzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, China.
Lei LyuQuzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, China.
Jia-Ling YouQuzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, China.
Shi-Teng HuangQuzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, China.
Bing-Dong ZhanQuzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter the relaxation of COVID‑19 containment measures, we investigated the pathogen spectrum and epidemiological characteristics of acute respiratory infections (ARIs) in Quzhou City from 2023 to 2024.

objectiveThis study aimed to investigate the pathogen spectrum and epidemiological characteristics of acute respiratory infections (ARIs) in Quzhou City from 2023 to 2024, providing a scientific basis for local prevention and control strategies.

methodsA total of 2,800 respiratory specimens were collected from November 2023 to July 2024, comprising 1,960 influenza-like illness (ILI) cases from outpatient/emergency departments and 840 severe acute respiratory infection (SARI) cases from inpatient departments. All samples were tested for 13 common respiratory pathogens using multiplex fluorescence quantitative PCR. Etiological and epidemiological analyses were performed based on detection results and case information.

resultsThe overall ARI positivity rate was 59.28% (1,660/2,800), with a male-to-female ratio of 1.07:1 (1,447/1,353). The three most prevalent pathogens were influenza virus (Flu, 23.21%, 650/2,800), Streptococcus pneumoniae (SP, 13.14%, 368/2,800), and adenovirus (ADV, 8.39%, 235/2,800). Single pathogen infections accounted for 73.55% (1,221/1,660) of positive cases, while co-infections with two or more pathogens accounted for 26.45% (439/1,660), yielding an overall co-infection rate of 15.68% (439/2,800). No significant gender difference was observed in detection rates. However, significant differences were found across case types, temporal periods, age groups, and geographic regions (P < 0.01). Children aged ≤5 years exhibited the highest positivity rate (78.00%, 378/525), while adults aged ≥65 years showed the lowest (34.53%, 144/417). Among surveillance regions, Kaihua County had the highest positivity rate (72.47%), and Changshan County the lowest (40.55%).

conclusionsMultiple respiratory pathogens and co-infections are prevalent in Quzhou City, with distinct age-specific and seasonal patterns. These findings underscore the need for continuous multi-pathogen surveillance and integrated prevention strategies for influenza and other respiratory infectious diseases in the post-pandemic era.

Indexed as

COVID-19Respiratory Tract InfectionsAdolescentAdultAgedChildChild, PreschoolChinaCoinfectionFemaleHumansInfantInfluenza, HumanMaleMiddle AgedSARS-CoV-2

Identifiers

PMID42258483
PMCPMC13245782

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.