Evidence map›Paper›PMID 42258411›Full record

ArticleAlcohol and alcoholism (Oxford, Oxfordshire)2026

Natural language processing of patient in-session speech to predict brief motivational interviewing alcohol intervention response: an exploratory study.

Mahmoud Elsayed, Kyla L Belisario, Ashley Blakely, Sabrina K Syan, Emily Levitt, Molly Garber, Emily MacKillop, Iris Balodis, Lawrence H Sweet, James MacKillop

Abstract read
In one paragraph

Article in Alcohol and alcoholism (Oxford, Oxfordshire), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Mahmoud ElsayedDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4L8, Canada.ORCID 0000-0001-6246-5071
Kyla L BelisarioDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4L8, Canada.
Ashley BlakelyPeter Boris Centre for Addictions Research, St. Joseph's Healthcare Hamilton, 100 West 5th Street, L9C 1G2, Hamilton, Canada.
Sabrina K SyanDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4L8, Canada.ORCID 0000-0002-1753-8478
Emily LevittPeter Boris Centre for Addictions Research, St. Joseph's Healthcare Hamilton, 100 West 5th Street, L9C 1G2, Hamilton, Canada.
Molly GarberDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4L8, Canada.ORCID 0000-0003-4595-6017
Emily MacKillopDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4L8, Canada.
Iris BalodisDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4L8, Canada.
Lawrence H SweetDepartment of Psychology, University of Georgia, 125 Baldwin St, 30602, Athens, GA, United States.
James MacKillopDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4L8, Canada.ORCID 0000-0002-8695-1071

Funding

Canada Research Chair in Translational Addiction Research CRC-2020-00170Gary R. Sperduto Chair in Clinical PsychologyNational Institute of Health R01AA025911Peter Boris Chair in Addictions Research
6 · The paper itself

Abstract

backgroundMotivational interviewing (MI) is a patient-centred, goal-oriented psychotherapy for alcohol use disorder (AUD) and numerous other conditions. While some language patterns have been linked to MI response, less is known about how broader linguistic features, sentiment, and engagement relate to post-intervention drinking. This study used natural language processing to examine these associations and clarify mechanisms through which MI for AUD exerts its effects.

methodsAdults with AUD (N = 68) completed a single MI session with structured feedback and discussion of potential drinking changes. Speech transcripts were analysed for change-, emotion-, motivation-, substance-, and health-related words. Sentiment analysis assessed emotional polarity, and engagement was measured by total words spoken. Linear regression models tested associations between linguistic features and drinking outcomes, including drinks/week, percent heavy drinking days (%HDD), and percent drinking days (%DD).

resultsParticipants showed significant reductions in drinks per week and %DD. Consistent with recent reviews of MI predictors, linguistic analyses found that greater use of change talk and health-related language was associated with more drinks per week at follow-up, whereas greater emotional talk and positive sentiment predicted fewer drinks per week. Health- and substance-related language predicted higher %HDD, while social motivation-related language predicted lower %DD. Term-frequency and multivariate analyses supported these patterns.

conclusionsVia natural language processing of MI speech, linguistic features such as motivational content and sentiment were linked to drinking outcomes. Findings demonstrate the potential of this approach as a scalable, data-driven complement to traditional coding systems, with applications for real-time feedback, clinician training, and personalized interventions.

Indexed as

AlcoholismMotivational InterviewingNatural Language ProcessingSpeechAdultFemaleHumansMaleMiddle AgedTreatment Outcomealcohol use disorderlinguistic patternsmotivational interviewingnatural language processingsentiment analysistreatment outcomes

Identifiers

PMID42258411
PMCPMC13245401

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.