Evidence map›Paper›PMID 42258372›Full record

ArticleMicrobiology (Reading, England)2026

Testing the drivers of environmental persistence in bacterial pathogens.

Sarah Marde Mehdiabad, John J Welch, Lucy A Weinert, Camille Bonneaud

Abstract read
In one paragraph

Article in Microbiology (Reading, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah Marde MehdiabadCentre for Ecology and Conservation, University of Exeter, Penryn, Cornwall TR10 9FE, UK.
John J WelchDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, UK.
Lucy A WeinertDepartment of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.
Camille BonneaudCentre for Ecology and Conservation, University of Exeter, Penryn, Cornwall TR10 9FE, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial pathogens can increase transmission opportunities by surviving in the external environment, but despite wide variation in this ability, the drivers of such differences remain poorly understood. Here, we comparatively analysed data from 47 studies on 29 bacterial pathogens to investigate how phylogeny, structural traits (cell wall structure), life history (transmission mode, lifestyle, generation time) and abiotic conditions (temperature, humidity and surface material) influence persistence following deposition on inert surfaces. Our results showed that bacterial species differ consistently in persistence, but not in a way predicted by phylogeny. Of the bacterial traits, cell wall structure had a significant effect, with Gram-positive bacteria showing longer survival times. In contrast, transmission mode, lifestyle and generation time had no consistent effect on persistence. Bacteria also survived longer on inorganic surfaces, but with no significant effect of temperature or humidity. These findings indicate that both bacterial structural traits and abiotic conditions may play crucial roles in shaping bacterial persistence in the environment, likely through effects on resistance to hypoosmotic stress. How the benefits of persisting in dry external environments, for instance, by harbouring a Gram-positive cell wall, trade off with survival in hyperosmotic conditions or in the face of immune defences, however, remain to be determined.

Indexed as

BacteriaEnvironmental MicrobiologyCell WallHumidityMicrobial ViabilityPhylogenyTemperatureabiotic conditionsbacteriacell wallecologyenvironmental persistencelife historytransmission mode

Identifiers

PMID42258372
PMCPMC13245882

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.