Evidence map›Paper›PMID 42258278›Full record

Trial reportPsychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors2026

A pilot randomized clinical trial evaluating the feasibility, acceptability, and preliminary efficacy of a cognitive-behavioral therapy adjunct to support benzodiazepine tapering among primary care patients coprescribed benzodiazepines and opioids.

Kate Wolitzky-Taylor, Michael Otto, Allison Metts, Maria Hanano, Larissa J Mooney

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kate Wolitzky-TaylorDepartment of Psychiatry and Biobehavioral Science, Semel Institute for Neuroscience and Human Behavior, Integrated Substance Use and Addiction Programs, University of California-Los Angeles.ORCID 0000-0001-6199-4350
Michael OttoDepartment of Psychologic and Brain Sciences, Boston University.
Allison MettsCentral Texas Veterans Healthcare System.
Maria HananoDepartment of Psychiatry and Biobehavioral Science, Semel Institute for Neuroscience and Human Behavior, Integrated Substance Use and Addiction Programs, University of California-Los Angeles.
Larissa J MooneyDepartment of Psychiatry and Biobehavioral Science, Semel Institute for Neuroscience and Human Behavior, Integrated Substance Use and Addiction Programs, University of California-Los Angeles.

Funding

Augmenting the Efficacy of Benzodiazepine Taper with Telehealth-Delivered Cognitive Behavioral Therapy for Anxiety Disorders in Patients Using Prescription OpioidsR21DA053394 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MOONEY, LARISSA JEANETTE, WOLITZKY-TAYLOR, KATE BASIA · 2022 to 2023
$360k
NIDA NIH HHSNIDA NIH HHS R21 DA053394
6 · The paper itself

Abstract

objectiveBenzodiazepine (BZ) use concerns have escalated in the wake of the opioid crisis, including increased overdose risk from co-use of BZ and opioids. Research evidence to inform clinical management of this issue is currently lacking.

methodThis pilot trial examined acceptability, feasibility, and preliminary efficacy of an intervention approach to reduce BZ use in adults who simultaneously take opioids. Forty participants with concomitant BZ and opioid prescriptions and significant anxiety symptoms were randomized to BZ taper with a cognitive-behavioral therapy protocol (BZT + CBT;

resultsBoth conditions were rated as logical (

conclusionsThe promising effect sizes obtained, along with evidence of adequate feasibility and acceptability, encourage further examination of the BZT + CBT approach. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Indexed as

Analgesics, OpioidAnxietyBenzodiazepinesCognitive Behavioral TherapyDrug TaperingAdultCombined Modality TherapyFeasibility StudiesFemaleHumansMaleMiddle AgedPatient Acceptance of Health CarePilot ProjectsPrimary Health CareTreatment OutcomeAnalgesics, OpioidBenzodiazepines

Identifiers

PMID42258278
PMCPMC13524120

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.