Evidence map›Paper›PMID 42258051›Full record

ArticleJournal of general internal medicine2026

Trends and Sex-Specific Rates of Obesity and Severe Obesity in US Hospitalized Adults, 2012-2021.

Jacob Lui, Karen M Fischer, Ruchi Gupta, Abhinav Singla, Aleksandra Murawska Baptista, Dominique Monlezun, Shant Ayanian, Cheˈ Matthew Harris, Sagar B Dugani

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Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jacob LuiDivision of Hospital Internal Medicine, Mayo Clinic, Rochester, MN, USA. jacob.lui@ucsf.edu.ORCID http://orcid.org/0000-0002-4854-0351
Karen M FischerDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-5037-6100
Ruchi GuptaDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0009-0009-5237-6396
Abhinav SinglaDivision of Hospital Internal Medicine, Mayo Clinic, Jacksonville, FL, USA.ORCID http://orcid.org/0000-0002-4643-431X
Aleksandra Murawska BaptistaDivision of Hospital Internal Medicine, Mayo Clinic, Jacksonville, FL, USA.ORCID http://orcid.org/0000-0002-8052-3578
Dominique MonlezunDivision of Hospital Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-7671-1886
Shant AyanianDivision of Hospital Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-9319-9001
Cheˈ Matthew HarrisDivision of General Internal Medicine, Johns Hopkins Bayview Medical Center, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-8010-9449
Sagar B DuganiDivision of Hospital Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-7858-1317

Funding

Rural Patient Risks and Exposures for Diabetes ConTrol (Rural PREDICT)K23MD016230 · NIMHD · MAYO CLINIC ROCHESTER · PI DUGANI, CHANDRASAGAR · 2021 to 2025
$763k
NIMHD NIH HHS K23 MD016230
6 · The paper itself

Abstract

backgroundRising national obesity rates may increase clinical and operational challenges for hospitals. However, trends and distributions in obesity and severe obesity among hospitalized adults are incompletely described.

objectiveTo examine trends in hospital-coded obesity and severe obesity rates among adults, by year, sex, age-groups, race/ethnicity, and US Census divisions.

designCross-sectional analyses of patients with hospital-coded obesity and severe obesity, using US National Inpatient Sample data, from 2012 through 2021. Rates were stratified by demographic group, and trends were calculated using logistic regression models, and prevalence ratios (PR) were used to compare male-to-female rates.

participantsHospitalized adults with obesity (body mass index [BMI] ≥ 30 kg/m MAIN MEASURE(S): Hospital-coded obesity and severe obesity rate per year, annual average change, absolute percent change, and PR of male-to-female obesity and severe obesity. KEY

resultsFrom 2012 through 2021, among 51,669,013 hospitalizations, 16.9% (n = 8,733,196) had hospital-coded obesity and 9.0% (n = 4,638,219) had severe obesity. Obesity rates increased from 13.0% to 21.4% (0.88% per year [95% CI, 0.81-0.95%], P < 0.001) while severe obesity rates increased from 6.6% to 11.2% (0.48% per year [95% CI, 0.43-0.53%], P < 0.001). Compared to other female age-groups and all male age-groups, females aged 30-49 years had the largest annual increase in obesity (1.25% [95% CI, 1.09-1.41%], P < 0.01) and severe obesity (0.95% [95% CI, 0.84-1.05%], P < 0.01). When compared across age and racial/ethnic groups, the largest sex differences in obesity rates were observed among adults aged 18-29 years, particularly of White (weighted average PR, 0.49 [95% CI, 0.48-0.49]) and Black (weighted average PR, 0.43 [95% CI, 0.43-0.44]) race.

conclusionsFrom 2012 through 2021, US hospital-coded obesity and severe obesity rates increased and revealed sex differences, underscoring the need for hospitals to adapt care delivery and operations.

Indexed as

hospitalizationobesitysevere obesitysex differences

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.