Evidence map›Paper›PMID 42258019›Full record

ArticleDiscover nano2026

Synthesis and characterization of magnetic nanoparticles loaded with curcumin and piperine and investigating the effects of these nanoparticles on Mir16-1 and mediators of apoptosis pathway in breast cancer.

Jalal Rezaeidian, Vahid Naseh, Maliheh Entezari, Hakimeh Ziyadi, Mehrdad Hashemi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discover nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jalal RezaeidianDepartment of Biology, Pa.C. Islamic Azad University, Parand, Iran.
Vahid NasehDepartment of Biology, Pa.C. Islamic Azad University, Parand, Iran.
Maliheh EntezariFarhikhtegan Medical Convergent Sciences Research Center, Farhikhtegan Hospital, Faculty of Medicine, TeMS.C, Islamic Azad University, Tehran, Iran. mentezari@iau.ac.ir.
Hakimeh ZiyadiDepartment of Organic Chemistry, Faculty of Pharmaceutical Chemistry, TeMS.C., Islamic Azad University, Tehran, Iran. behnazziyadi@yahoo.com.
Mehrdad HashemiFarhikhtegan Medical Convergent Sciences Research Center, Farhikhtegan Hospital, Faculty of Medicine, TeMS.C, Islamic Azad University, Tehran, Iran. mhashemi@iau.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curcumin (CUR) and piperine (PIP), as natural polyphenols, exhibit potent anti-cancer effects against many cancers, such as breast cancer. To enhance the efficiency of these drugs when used together and to impart magnetic properties to targeted drug delivery, CUR and PIP were loaded on magnetic iron nanoparticles (NPs) coated with silica (Fe

Indexed as

Breast cancerCurcuminFlow cytometryMagnetic nanoparticlesMir16-1MTT assayPiperine

Identifiers

PMID42258019
PMCPMC13247014

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.