ArticleJACC. Case reports2026
Hydroxychloroquine Cardiotoxicity Confirmed by Electron Microscopy: The Myocarditis Mimic.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
backgroundHydroxychloroquine (HCQ) is widely used for autoimmune disease, but rare cardiotoxicity can mimic inflammatory cardiomyopathy. CASE SUMMARY: A 79-year-old woman on 10 years of HCQ presented with fatigue, dizziness, and exertional dyspnea and was found to have low cardiac output (1.75 L/min) and cardiac index (1.01 L/min/m DISCUSSION: HCQ cardiotoxicity may resemble myocarditis on imaging. Biopsy with electron microscopy confirms the diagnosis and guides management. TAKE-HOME MESSAGES: Maintain suspicion for HCQ toxicity despite inflammatory imaging patterns. Early tissue diagnosis and drug discontinuation may prevent progression and support recovery.
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