Evidence map›Paper›PMID 42257485›Full record

Observational studyClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

AngioJet Rheolytic Thrombectomy Combined with Glycoprotein IIb/IIIa Inhibitors in Acute Myocardial Infarction: An Observational Study.

Yi-Xiong Huang, Yi Cao, Yu Chen, Yi-Gang Qiu, Ying-Ming Liu, Jiang-Chun He, Li Zhao, Yong Xu

Abstract readObservational Study
In one paragraph

Observational study in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi-Xiong HuangMedical School of Chinese People's Liberation Army General Hospital, 28 Fuxing Road, Haidian District, Peking, 100853, People's Republic of China.ORCID 0000-0003-4936-1934
Yi CaoDepartment of Cardiology, Sixth Medical Center of Chinese People's Liberation Army General Hospital, 6 Fucheng Road, Haidian District, Peking, Beijing, 100048, People's Republic of China.
Yu ChenDepartment of Cardiology, Sixth Medical Center of Chinese People's Liberation Army General Hospital, 6 Fucheng Road, Haidian District, Peking, Beijing, 100048, People's Republic of China.
Yi-Gang QiuDepartment of Cardiology, Sixth Medical Center of Chinese People's Liberation Army General Hospital, 6 Fucheng Road, Haidian District, Peking, Beijing, 100048, People's Republic of China.
Ying-Ming LiuDepartment of Cardiology, Sixth Medical Center of Chinese People's Liberation Army General Hospital, 6 Fucheng Road, Haidian District, Peking, Beijing, 100048, People's Republic of China.
Jiang-Chun HeDepartment of Cardiology, Sixth Medical Center of Chinese People's Liberation Army General Hospital, 6 Fucheng Road, Haidian District, Peking, Beijing, 100048, People's Republic of China.
Li ZhaoDepartment of Cardiology, Sixth Medical Center of Chinese People's Liberation Army General Hospital, 6 Fucheng Road, Haidian District, Peking, Beijing, 100048, People's Republic of China.
Yong XuDepartment of Cardiology, Sixth Medical Center of Chinese People's Liberation Army General Hospital, 6 Fucheng Road, Haidian District, Peking, Beijing, 100048, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivesThis study aimed to evaluate the efficacy and safety of AngioJet rheolytic thrombectomy with the adjunctive use of glycoprotein IIb/IIIa inhibitors (GPI) in the setting of ST-segment elevation myocardial infarction (STEMI).MethodsWe conducted a retrospective cohort study of 877 consecutive patients with STEMI. Propensity score matching (PSM) was employed to balance the baseline characteristics between the group receiving AngioJet rheolytic thrombectomy plus GPI (the AT + GPI group) and those receiving routine treatment (the RT group). The primary endpoint was major adverse cardiovascular and cerebrovascular events (MACCE) at 1 year. Safety endpoints comprised any bleeding and major bleeding events.ResultsNinety-seven patients received AngioJet rheolytic thrombectomy and GPI. No significant differences were observed between the two groups regarding in-hospital mortality, reinfarction, stent thrombosis, stroke, or bleeding. After propensity-score matching, the cumulative incidence of MACCE at 1 year did not differ significantly between the AT + GPI group and the RT group (8.2% vs 9.3%; hazard ratio, 0.894; 95% CI, 0.345 to 2.318; p = 0.818). The incidence rates of all individual safety endpoints-including stroke and bleeding-showed no significant differences between the two groups.ConclusionsIn this observational cohort of STEMI patients, the strategy of combining AngioJet rheolytic thrombectomy with GPI was not associated with improved 1-year outcomes compared to routine treatment, though it did not increase bleeding or stroke risk.

Indexed as

Myocardial InfarctionPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexThrombectomyAgedFemaleHumansMaleMiddle AgedRetrospective StudiesPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa Complexpercutaneous coronary interventionplatelet glycoprotein IIb/IIIa inhibitorspropensity-score matchingSTEMIthrombectomy

Identifiers

PMID42257485
PMCPMC13247286

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.