ReviewPolymer science & technology (Washington, D.C.)2025
Synthetic Polymers for Drug, Gene, and Vaccine Delivery.
Review in Polymer science & technology (Washington, D.C.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Feasibility of Polylactic Acid-Polycaprolactone-Blended Microspheres in Transarterial Embolization Therapy.ACS omega · 2026Article
- Engineered Xenogeneic Bone Scaffold with IL-10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Injectable dual-affinity self-assembling peptide hydrogels for local controlled delivery of therapeutic antibodies.Asian journal of pharmaceutical sciences · 2026Article
- Antioxidant Proline Carbon Dot-Composited Poly(L-methionine) Hydrogel Restores Mitophagy to Alleviate Cellular Senescence in Intervertebral Disc Degeneration.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- High-Yield Synthesis of Molecular Bottlebrushes With Block Copolymer Side Chains by the Copper Superoxido Complex Enabled ATRP via a Grafting-From Approach.Macromolecular rapid communications · 2026Article
- Engineering Polymeric Nano-PROTAC for Targeted Protein Degradation and Cancer Therapy.Polymer science & technology (Washington, D.C.) · 2026Review
- Novel Composite Conduits for Long-Distance Peripheral Nerve Repair.Polymer science & technology (Washington, D.C.) · 2026Article
- Spatiotemporal activation of unfolded protein response by combined sonodynamic therapy and proteasome inhibition with bortezomib-conjugated TiN nanoparticles.Bioactive materials · 2026Article
- Biomimetic LHRH-targeted nanogels for spatiotemporal-enhanced chemo-dynamic therapy of cancer.Journal of nanobiotechnology · 2026Article
- The application of nanoparticle-mediated siRNA delivery systems in ovarian cancer.Cancer gene therapy · 2026Review
- Biomimetic PD-1 macrophage nanoplatform for Cip2a silencing and immune activation in oral squamous cell carcinoma.Journal of nanobiotechnology · 2026Article
- Spatiotemporal Nanotransformers for Antitumoral Orchestration of Protein Homeostasis.Polymer science & technology (Washington, D.C.) · 2026Article
- Peptide-Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Boosting cancer therapy with self-assembled inorganic nanocarriers via host-guest chemistry.Materials today. Bio · 2026Review
- Fusogenic Polymer-Liposome-Hybrid Nanoparticle: A Versatile Platform for Synchronized Drug Delivery to the Cytoplasm and Cell Membrane.Polymer science & technology (Washington, D.C.) · 2026Article
- Biocatalytic Nanoregulators Restore Joint Redox-Immune Homeostasis in Rheumatoid Arthritis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Polysulfone Membranes: Here, There and Everywhere.Membranes · 2026Review
- The role of an ultrasound-responsive injectable piezoelectric hydrogel in promoting nerve regeneration and alleviating neuropathic pain.Theranostics · 2026Article
- Photocrosslinkable Chitosan Quaternary Ammonium Salt-Based Ternary Hydrogel with Fibroblast Growth Factor 21 for Diabetic Wound Healing.Biomaterials research · 2026Article
- Emodin-Based Drug Delivery Systems: Therapeutic Applications in Inflammatory Diseases.International journal of nanomedicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synthetic polymers have emerged as crucial materials for drug, gene, and vaccine delivery, offering versatile platforms for enhancing therapeutic efficacy and safety. This review provides a comprehensive overview of various synthetic polymers, including polyesters, polycarbonates, polyanhydrides, polypeptides, and polyethers, emphasizing their preparation methods and functional properties. We discuss the application of these polymers for the controlled delivery of small molecules, peptides, and proteins, highlighting their therapeutic benefits and action mechanisms. Furthermore, we explore the advances in gene delivery technologies, including plasmid DNA, oligonucleotides, and mRNA-based approaches. The review also addresses the role of synthetic polymers in vaccine delivery, focusing on protein and mRNA vaccines. By synthesizing current knowledge, we aim to outline the significant contributions of synthetic polymers to modern therapeutics and identify future directions for research in the biomedical fields.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.