Evidence map›Paper›PMID 42257112›Full record

ArticleJournal of family medicine and primary care2026

Clinical and laboratory indicators of severe scrub typhus in adults: Insights from a retrospective study in a teaching hospital in South India.

L Lourde Raja, Premkumar Ramasubramani, A Srividya, D Senkadhirdasan, R Prahankumar, Karthikeyan Kadirvel, Abhijit Vinodrao Boratne, K Vanathy, Agieshkumar Balakrishna Pillai

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Article in Journal of family medicine and primary care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

L Lourde RajaDepartment of Community Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Puducherry, India.
Premkumar RamasubramaniDepartment of Community Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Puducherry, India.
A SrividyaIndian Council of Medical Research-Vector Control Research Centre, Puducherry, India.
D SenkadhirdasanDepartment of Community Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Puducherry, India.
R PrahankumarDepartment of Community Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Puducherry, India.
Karthikeyan KadirvelDepartment of Paediatrics, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Puducherry, India.
Abhijit Vinodrao BoratneDepartment of Community and Family Medicine, All India Institute of Medical Sciences, Deoghar, Jharkhand, India.
K VanathyDepartment of Microbiology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Puducherry, India.
Agieshkumar Balakrishna PillaiDepartment of Clinical Virology, Institute of Advanced Virology, Thiruvananthapuram, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Scrub typhus, caused by Objective: To identify the clinical and laboratory predictors associated with the severity of scrub typhus in patients admitted to a teaching hospital in Puducherry, South India. Materials and Methods: A retrospective analysis was conducted on scrub typhus patients aged 18 years and above admitted to Mahatma Gandhi Hospital, Puducherry, from 2019 to 2023. IgM ELISA confirmed diagnosis. Statistical tests identified clinical and laboratory predictors associated with severe disease outcomes. Results: Among 546 scrub typhus cases, 44.1% were males and 55.9% females, with a mean age of 47.1 years. High-grade fever (87.9%) and eschar (44.1%) were the most common symptoms. Significant predictors of severity included diabetes mellitus ( Conclusion: This study underscores the public health burden of scrub typhus, emphasizing severe complications like myocarditis and pneumonia. Identifying key predictors, such as diabetes, skin rash, and severe anemia, is crucial for early recognition and timely intervention to reduce mortality and manage the disease effectively.

Indexed as

Clinical manifestationsdiabetes mellitusOrientia tsutsugamushiscrub typhussevere disease predictors

Identifiers

PMID42257112
PMCPMC13241171

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.