Evidence map›Paper›PMID 42257036›Full record

ArticleFrontiers in cardiovascular medicine2026

Risk-score performance for detecting transthyretin cardiac amyloidosis in severe aortic stenosis: a prospective cohort study.

Graczyk Katarzyna, Dziewięcka Ewa, Winiarczyk Mateusz, Stępień Agnieszka, Przytuła Natalia, Holcman Katarzyna, Wiśniowska-Śmiałek Sylwia, Szot Wojciech, Kostkiewicz Magdalena, Rubiś Paweł

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Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Graczyk KatarzynaDoctoral School of Medical and Health Sciences, Jagiellonian University Medical College, Krakow, Poland.
Dziewięcka EwaClinical Department of Cardiac and Vascular Diseases, John Paul II Hospital, Krakow, Poland.
Winiarczyk MateuszDoctoral School of Medical and Health Sciences, Jagiellonian University Medical College, Krakow, Poland.
Stępień AgnieszkaDoctoral School of Medical and Health Sciences, Jagiellonian University Medical College, Krakow, Poland.
Przytuła NataliaDoctoral School of Medical and Health Sciences, Jagiellonian University Medical College, Krakow, Poland.
Holcman KatarzynaDepartment of Nuclear Medicine, John Paul II Hospital, Kraków, Poland.
Wiśniowska-Śmiałek SylwiaClinical Department of Cardiac and Vascular Diseases, John Paul II Hospital, Krakow, Poland.
Szot WojciechDepartment of Nuclear Medicine, John Paul II Hospital, Kraków, Poland.
Kostkiewicz MagdalenaClinical Department of Cardiac and Vascular Diseases, John Paul II Hospital, Krakow, Poland.
Rubiś PawełClinical Department of Cardiac and Vascular Diseases, John Paul II Hospital, Krakow, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The coexistence of transthyretin cardiac amyloidosis (ATTR-CA) and severe aortic stenosis (AS) presents a diagnostic challenge. This study aimed to determine the prevalence of this dual pathology and to assess the effectiveness of diagnostic models in enhancing detection accuracy. Methods: We conducted a prospective study of 104 consecutive patients with severe AS (aortic valve area <1 cm Results: Nineteen (18%) patients with AS also had ATTR-CA (ATTR-CA-AS). They were significantly older (82.6 ± 7.4 vs. 76 ± 6.9, Conclusions: ATTR-CA is commonly observed in patients with severe AS. Implementing risk scores in routine practice could enhance the diagnostic accuracy of ATTR-CA in patients with AS, given their strong diagnostic performance and ease of assessment.

Indexed as

amyloidosisaortic stenosisATTR-CAscoreTAVI

Identifiers

PMID42257036
PMCPMC13236916

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