ArticleClinical case reports2026
Intracranial Solitary Fibrous Tumors With Glandular and Papillary Structures: A Case Report.
Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Solitary fibrous tumor (SFT) is a fibroblastic neoplasm with NAB2 and STAT6 gene fusion as well as STAT6 nuclear expression. Uncommon variants of intracranial SFTs, such as glandular and papillary structures, are extremely rare. We present a rare SFT case in a 64-year-old female demonstrating unprecedented glandular structures and extensive myxoid stromal changes. This morphologic divergence underscores the imperative for molecular validation in SFTs with atypical histologic features. Our findings advocate a refined diagnostic protocol: RNA-based next-generation sequencing (RNA-NGS) must be prioritized in STAT6-immunopositive central nervous system (CNS) mesenchymal tumors when DNA-NGS fails to identify the pathognomonic NAB2::STAT6 fusion, as demonstrated by the resolution of diagnostic ambiguity through detection of a cryptic NAB2-exon4::STAT6-UTR fusion in this case.
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