Evidence map›Paper›PMID 42256945›Full record

ArticleClinical case reports2026

A Diagnostic Challenge: From Suspected Ischemic Stroke to Confirmed Herpetic Encephalitis.

Mafalda Dias Neves, Miguel Gonçalves Pereira, Natacha Silveira, Susana Barbosa, José Maria Matos Sousa, Eduarda Pereira, Elisabete Monteiro

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mafalda Dias NevesIntensive Care Medicine Department Unidade Local de Saúde de Castelo Branco E.P.E., Hospital Amato Lusitano Castelo Branco Portugal.
Miguel Gonçalves PereiraIntensive Care Medicine Department Unidade Local de Saúde da Guarda E.P.E., Hospital Sousa Martins Guarda Portugal.ORCID https://orcid.org/0009-0008-7052-6653
Natacha SilveiraIntensive Care Medicine Department Unidade Local de Saúde Do Algarve E.P.E., Hospital de Faro Guarda Portugal.ORCID https://orcid.org/0009-0004-6049-1996
Susana BarbosaIntensive Care Medicine Department Unidade Local de Saúde de São João E.P.E., Hospital São João Porto Portugal.
José Maria Matos SousaDepartment of Neuroradiology Unidade Local de Saúde de São João Hospital São João E.P.E Porto Portugal.
Eduarda PereiraIntensive Care Medicine Department Unidade Local de Saúde de São João E.P.E., Hospital São João Porto Portugal.
Elisabete MonteiroIntensive Care Medicine Department, Unidade Local de Saúde de São João E.P.E, Hospital São João, Porto, Portugal; Faculty of Medicine University of Porto (FMUP) Porto, Portugal; RISE - Health Unit, FMUP Porto Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HSVE mimics large-vessel stroke with focal deficits and altered consciousness, challenging early diagnosis: Hemorrhagic lesions outside vascular territories warrant urgent lumbar puncture and empiric acyclovir initiation; Malignant edema may require decompressive craniectomy as a life-saving intervention. Outcomes vary, but prompt neurosurgical evaluation is essential when intracranial hypertension persists.

Indexed as

acyclovirDecompressive craniectomyherpes simplex encephalitisNeurocritical carestroke mimic

Identifiers

PMID42256945
PMCPMC13239893

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.