ArticleClinical medicine insights. Case reports2026
Extrahepatic Biliary Atresia With Situs Inversus and Ventricular Septal Defect: A Case Report.
Article in Clinical medicine insights. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Biliary atresia is a rare, progressive cholangiopathy of infancy and a leading cause of pediatric liver failure. Syndromic forms associated with laterality defects and congenital heart disease are uncommon and pose diagnostic challenges. Case Presentation: A 3-month-old female infant, born at term via home delivery to a consanguineous couple, presented with persistent jaundice since birth. Examination revealed icterus, anemia, hepatomegaly, and a pansystolic murmur. Laboratory tests showed conjugated hyperbilirubinemia, elevated liver enzymes, and coagulopathy, while infectious, metabolic, and endocrine causes were excluded. Imaging revealed a small gallbladder with a triangular cord sign, biliary obstruction on HIDA scan, and situs inversus. Echocardiography identified a small perimembranous ventricular septal defect. Percutaneous liver biopsy confirmed bile duct proliferation, fibrosis, and cholestasis, consistent with extrahepatic biliary atresia. Diagnostic Assessment: Syndromic biliary atresia was diagnosed based on clinical, radiological, and histopathological findings, with associated situs inversus and a congenital heart defect. Therapeutic Intervention and Outcome: The patient received supportive care including vitamin K and nutritional supplementation. Pediatric surgical consultation was obtained; however, in view of advanced fibrosis, the syndromic constellation, and the family's decision to decline operative intervention after counseling, Kasai portoenterostomy was not performed. Liver transplantation was discussed but declined by the family. The infant's condition deteriorated and she died approximately one month after diagnosis from complications of advanced liver disease. Conclusion: Early recognition of biliary atresia and its syndromic associations is crucial. Delayed presentation and limited access to specialized care can adversely affect outcomes, underscoring the need for timely diagnosis, multidisciplinary evaluation, and family counseling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.