Evidence map›Paper›PMID 42256608›Full record

ArticleDEN open2027

Endoscopic Pseudo-dilation of Esophagogastric Junction During Peroral Endoscopic Myotomy: (With Video).

Kei Ushikubo, Haruhiro Inoue, Ippei Tanaka, Nikko Raymundo, Kazuki Yamamoto, Yuta Tamaru, Kohei Shigeta, Satoshi Abiko, Yohei Nishikawa, Mayo Tanabe and 4 more

Abstract read
In one paragraph

Article in DEN open, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kei UshikuboDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Haruhiro InoueDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Ippei TanakaDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Nikko RaymundoDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Kazuki YamamotoDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Yuta TamaruDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Kohei ShigetaDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Satoshi AbikoDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Yohei NishikawaDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Mayo TanabeDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Manabu OnimaruDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Koji OtukaDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Takayoshi ItoDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.
Noboru YokoyamaDigestive Disease Center Showa Medical University Koto Toyosu Hospital Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: During peroral endoscopic myotomy (POEM) for achalasia, endoscopic esophagogastric junction (EGJ) opening is generally considered a sign of successful myotomy. However, in clinical practice, the EGJ may appear to open immediately after submucosal tunneling, even before myotomy is performed. We defined this phenomenon as pseudo-dilation and evaluated changes in EGJ appearance during POEM. Methods: This retrospective study included 65 consecutive patients who underwent POEM between February and June 2025. Endoscopic images obtained at three stages-before POEM, after submucosal tunneling, and after myotomy-were evaluated using a three-tier Endoscopic Junctional Dilation (EJD) grade. Differences in EJD grade across procedural stages were analyzed using the Friedman test, with post hoc Wilcoxon signed-rank tests and Bonferroni correction. The Bickenböller statistic was used as a complementary analysis. Two certified endoscopists independently evaluated all images, and interobserver agreement was assessed using Cohen's κ and weighted κ. Results: The EJD grade increased significantly after submucosal tunneling compared with before POEM ( Conclusion: Pseudo-dilation of the EGJ was commonly observed immediately after submucosal tunneling during POEM. Trial Registration: N/A.

Indexed as

endoscopyesophageal achalasiaesophageal motility disorderslower esophageal sphinctermyotomy

Identifiers

PMID42256608
PMCPMC13239068

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.