ArticleFrontiers in neurology
Risk factors for early neurological deterioration in patients with acute ischaemic stroke and assessment of short-term prognosis.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To identify independent risk factors for early neurological deterioration (END) in patients with acute ischaemic stroke (AIS) and evaluate its impact on short-term clinical outcomes. Methods: A total of 186 AIS patients admitted between January 2023 and January 2025 were retrospectively enrolled and divided into an END group ( Results: The END group showed significantly higher admission NIHSS score, fasting plasma glucose, glycated hemoglobin, homocysteine, high-sensitivity C-reactive protein (hs-CRP), D-dimer, and greater proportions of hypertension, diabetes mellitus, atrial fibrillation, large artery atherosclerosis, cardioembolic subtypes, and large infarction (all Conclusions: Higher admission NIHSS score, fasting plasma glucose, hs-CRP, D-dimer, atrial fibrillation, and large infarction are independent risk factors for END in AIS. END is associated with worse neurological recovery, prolonged hospitalization, and higher 3-month mortality. Early identification of high-risk patients and targeted intervention are essential for improving outcomes.
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