Evidence map›Paper›PMID 42256546›Full record

ArticleHemaSphere2026

Varnimcabtagene autoleucel (ARI-0001) in relapsed or refractory mantle cell lymphoma.

Nil Albiol, Nuria Martínez-Cibrián, Amanda Isabel Pérez, Sergio Navarro-Velázquez, Guilherme Muzzi, Aina Oliver-Caldes, Marta Español-Rego, Leticia Alserawan, Mercedes Montoro-Lorite, Carla Ramos and 32 more

Abstract read
In one paragraph

Article in HemaSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors.

Nil AlbiolDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.ORCID https://orcid.org/0000-0003-2942-1362
Nuria Martínez-CibriánDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Amanda Isabel PérezDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Sergio Navarro-VelázquezFundació de Recerca Clínic Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Barcelona Spain.
Guilherme MuzziDepartment of Hematology Hospital da Policia Militar de Minas Gerais Belo Horizonte Minas Gerais Brazil.
Aina Oliver-CaldesDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Marta Español-RegoFundació de Recerca Clínic Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Barcelona Spain.
Leticia AlserawanFundació de Recerca Clínic Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Barcelona Spain.
Mercedes Montoro-LoriteDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Carla RamosDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Pilar AyoraDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Ana África Martin-LópezDepartment of Hematology Hospital Universitario de Salamanca Salamanca Spain.
Almudena CaberoDepartment of Hematology Hospital Universitario de Salamanca Salamanca Spain.
Estefanía Pérez-LópezDepartment of Hematology Hospital Universitario de Salamanca Salamanca Spain.
Alejandro Martín García-SanchoDepartment of Hematology Hospital Universitario de Salamanca Salamanca Spain.
Tycho BaumannDepartment of Hematology Hospital Universitario 12 de Octubre, Instituto de Investigación Hospital 12 Octubre (I+12) Madrid Spain.
José María Sánchez-PinaDepartment of Hematology Hospital Universitario 12 de Octubre, Instituto de Investigación Hospital 12 Octubre (I+12) Madrid Spain.
Anabelle ChineaDepartment of Hematology Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) Madrid Spain.
Paula Fernández-CaldasDepartment of Hematology Hospital Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM) Madrid Spain.
Mariana Bastos-OreiroDepartment of Hematology Hospital Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM) Madrid Spain.ORCID https://orcid.org/0000-0002-9431-4646
Mi KwonDepartment of Hematology Hospital Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM) Madrid Spain.
Luis Gerardo Rodríguez-LobatoDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Laura MagnanoDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Andrea RiveroDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Juan G CorreaDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Pablo MozasDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.ORCID https://orcid.org/0000-0001-9528-4971
María Sánchez-CastañónDepartment of Immunology Hospital Clínic de Barcelona Barcelona Spain.
Juan J Mata-MolanesFundació de Recerca Clínic Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Barcelona Spain.
Paola CharryApheresis Unit Hospital Clínic de Barcelona Barcelona Spain.
Jose R ÁlamoHematopathology Section, Pathology Department Hospital Clínic de Barcelona Barcelona Spain.
Xavier SetoaínFundació de Recerca Clínic Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Barcelona Spain.
Sonia RodríguezDepartment of Radiology Hospital Clínic de Barcelona Barcelona Spain.
Eulalia OlestiFundació de Recerca Clínic Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Barcelona Spain.
Joaquín Sáez-PeñataroFundació de Recerca Clínic Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Barcelona Spain.
Carlos Fernández de LarreaDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.ORCID https://orcid.org/0000-0003-4930-9255
Álvaro Urbano-IspizuaDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Armando López-GuillermoDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Julio DelgadoDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.ORCID https://orcid.org/0000-0002-5157-4376
E Azucena González-NavarroFundació de Recerca Clínic Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Barcelona Spain.
Manel JuanFundació de Recerca Clínic Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Barcelona Spain.
Eva GinéDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.
Valentín Ortiz-MaldonadoDepartment of Hematology Hospital Clínic de Barcelona Barcelona Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varnimcabtagene autoleucel (var-cel) is an autologous CD19-directed chimeric antigen receptor (CAR) T-cell therapy administered using an adaptive, fractionated dosing strategy. We conducted a multicenter retrospective study to evaluate the safety and efficacy of var-cel in patients with relapsed or refractory (R/R) mantle cell lymphoma (MCL) treated at four Spanish centers, including patients enrolled in the CART19-BE-01 trial and a subsequent compassionate use program. Thirty patients underwent leukapheresis; 27 received var-cel following lymphodepletion and fractionated infusion in three escalating doses (0.1 to 5 × 10

Identifiers

PMID42256546
PMCPMC13240006

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.