Evidence map›Paper›PMID 42256507›Full record

ArticleEvolutionary applications2026

Genome-Wide Homozygosity Predicts Inbreeding Depression in the Hihi/Stitchbird (

Hui Zhen Tan, Katarina C Stuart, Joseph Guhlin, Tram Vi, Selina Patel, Laura Duntsch, John G Ewen, Patricia Brekke, Anna W Santure

Abstract read
In one paragraph

Article in Evolutionary applications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hui Zhen TanSchool of Biological Sciences University of Auckland Auckland New Zealand.ORCID https://orcid.org/0000-0002-6750-7506
Katarina C StuartSchool of Biological Sciences University of Auckland Auckland New Zealand.ORCID https://orcid.org/0000-0002-0386-4600
Joseph GuhlinGenomics Aotearoa, Biochemistry Department, School of Biomedical Sciences University of Otago Dunedin New Zealand.ORCID https://orcid.org/0000-0003-3264-7178
Tram ViSchool of Biological Sciences University of Auckland Auckland New Zealand.ORCID https://orcid.org/0000-0002-4319-5544
Selina PatelSchool of Biological Sciences University of Auckland Auckland New Zealand.ORCID https://orcid.org/0009-0007-4695-5127
Laura DuntschLivestock Improvement Corporation Ltd Hamilton New Zealand.ORCID https://orcid.org/0000-0002-4347-456X
John G EwenInstitute of Zoology Zoological Society of London London UK.ORCID https://orcid.org/0000-0001-6402-1378
Patricia BrekkeInstitute of Zoology Zoological Society of London London UK.ORCID https://orcid.org/0000-0001-6298-3194
Anna W SantureSchool of Biological Sciences University of Auckland Auckland New Zealand.ORCID https://orcid.org/0000-0001-8965-1042

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Population declines result in increasingly small populations, which often experience an increase in inbreeding. Inbreeding may be negatively associated with fitness traits like survival and reproduction, that is, inbreeding depression, and is therefore detrimental to population persistence and adaptive potential. Realised genetic load-the count of homozygous deleterious alleles-is increasingly used as a proxy for fitness when investigating inbreeding depression. However, assessing the limitations of genetic load in predicting fitness, and comparisons with other homozygosity and inbreeding metrics, are needed. Our study system is the hihi/stitchbird (

Indexed as

fitnessgenetic loadhihihomozygosityinbreedinginbreeding depression

Identifiers

PMID42256507
PMCPMC13240288

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.