ArticleSage open pediatrics
Earlier Onset of Subacute Sclerosing Panencephalitis in Bangladeshi Children: Insights from a Case Series.
Article in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Subacute sclerosing panencephalitis (SSPE) is a fatal neurodegenerative complication of measles, characterized by a progressive decline in neurological function. This case series described 42 children diagnosed with SSPE and received treatment at a tertiary neurology hospital in Dhaka, Bangladesh, from the year 2019 to 2021. The median age at onset of was 4 years (range: 2.5-11 years), with a mean latent period of 2.68 ± 0.97 (SD) years. While 30 cases (71.4%) were immunized, 23 of these children developed SSPE despite receiving immunization after 9 months of age. Additionally, a small proportion of cases (n = 7) had a history of measles infection prior to the scheduled age of vaccination. Males predominated (88.1%) in this cohort. Clinical presentation typically involved speech and motor regression alongside the myoclonic jerks. These findings point toward an earlier onset and shorter latency period of SSPE in this population which demands further evaluation.
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